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427 results

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Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.
Haure-Mirande JV, Audrain M, Fanutza T, Kim SH, Klein WL, Glabe C, Readhead B, Dudley JT, Blitzer RD, Wang M, Zhang B, Schadt EE, Gandy S, Ehrlich ME. Haure-Mirande JV, et al. Among authors: schadt ee. Acta Neuropathol. 2017 Nov;134(5):769-788. doi: 10.1007/s00401-017-1737-3. Epub 2017 Jun 13. Acta Neuropathol. 2017. PMID: 28612290 Free PMC article.
CR1 and the "vanishing amyloid" hypothesis of Alzheimer's disease.
Gandy S, Haroutunian V, DeKosky ST, Sano M, Schadt EE. Gandy S, et al. Among authors: schadt ee. Biol Psychiatry. 2013 Mar 1;73(5):393-5. doi: 10.1016/j.biopsych.2013.01.013. Biol Psychiatry. 2013. PMID: 23399469 Free PMC article. No abstract available.
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, MacDonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ, Gudnason V, Myers AJ, Schadt EE, Neumann H, Zhu J, Emilsson V. Zhang B, et al. Among authors: schadt ee. Cell. 2013 Apr 25;153(3):707-20. doi: 10.1016/j.cell.2013.03.030. Cell. 2013. PMID: 23622250 Free PMC article.
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases.
Narayanan M, Huynh JL, Wang K, Yang X, Yoo S, McElwee J, Zhang B, Zhang C, Lamb JR, Xie T, Suver C, Molony C, Melquist S, Johnson AD, Fan G, Stone DJ, Schadt EE, Casaccia P, Emilsson V, Zhu J. Narayanan M, et al. Among authors: schadt ee. Mol Syst Biol. 2014 Jul 30;10(7):743. doi: 10.15252/msb.20145304. Mol Syst Biol. 2014. PMID: 25080494 Free PMC article.
Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease.
Talukdar HA, Foroughi Asl H, Jain RK, Ermel R, Ruusalepp A, Franzén O, Kidd BA, Readhead B, Giannarelli C, Kovacic JC, Ivert T, Dudley JT, Civelek M, Lusis AJ, Schadt EE, Skogsberg J, Michoel T, Björkegren JL. Talukdar HA, et al. Among authors: schadt ee. Cell Syst. 2016 Mar 23;2(3):196-208. doi: 10.1016/j.cels.2016.02.002. Epub 2016 Mar 3. Cell Syst. 2016. PMID: 27135365 Free PMC article.
Development and clinical application of an integrative genomic approach to personalized cancer therapy.
Uzilov AV, Ding W, Fink MY, Antipin Y, Brohl AS, Davis C, Lau CY, Pandya C, Shah H, Kasai Y, Powell J, Micchelli M, Castellanos R, Zhang Z, Linderman M, Kinoshita Y, Zweig M, Raustad K, Cheung K, Castillo D, Wooten M, Bourzgui I, Newman LC, Deikus G, Mathew B, Zhu J, Glicksberg BS, Moe AS, Liao J, Edelmann L, Dudley JT, Maki RG, Kasarskis A, Holcombe RF, Mahajan M, Hao K, Reva B, Longtine J, Starcevic D, Sebra R, Donovan MJ, Li S, Schadt EE, Chen R. Uzilov AV, et al. Among authors: schadt ee. Genome Med. 2016 Jun 1;8(1):62. doi: 10.1186/s13073-016-0313-0. Genome Med. 2016. PMID: 27245685 Free PMC article.
427 results