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Inhibition of ceramide de novo synthesis by myriocin produces the double effect of reducing pathological inflammation and exerting antifungal activity against A. fumigatus airways infection.
Caretti A, Torelli R, Perdoni F, Falleni M, Tosi D, Zulueta A, Casas J, Sanguinetti M, Ghidoni R, Borghi E, Signorelli P. Caretti A, et al. Among authors: signorelli p. Biochim Biophys Acta. 2016 Jun;1860(6):1089-97. doi: 10.1016/j.bbagen.2016.02.014. Epub 2016 Feb 24. Biochim Biophys Acta. 2016. PMID: 26922830
Breast cancer and sphingolipid signalling.
Signorelli P, Ghidoni R. Signorelli P, et al. J Dairy Res. 2005;72 Spec No:5-13. doi: 10.1017/s0022029905001238. J Dairy Res. 2005. PMID: 16180715 Review. No abstract available.
Myriocin treatment of CF lung infection and inflammation: complex analyses for enigmatic lipids.
Caretti A, Vasso M, Bonezzi FT, Gallina A, Trinchera M, Rossi A, Adami R, Casas J, Falleni M, Tosi D, Bragonzi A, Ghidoni R, Gelfi C, Signorelli P. Caretti A, et al. Among authors: signorelli p. Naunyn Schmiedebergs Arch Pharmacol. 2017 Aug;390(8):775-790. doi: 10.1007/s00210-017-1373-4. Epub 2017 Apr 24. Naunyn Schmiedebergs Arch Pharmacol. 2017. PMID: 28439630
64 results