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Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR. Lacampagne A, et al. Among authors: bauer c. Acta Neuropathol. 2017 Nov;134(5):749-767. doi: 10.1007/s00401-017-1733-7. Epub 2017 Jun 19. Acta Neuropathol. 2017. PMID: 28631094 Free article.
The β-secretase-derived C-terminal fragment of βAPP, C99, but not Aβ, is a key contributor to early intraneuronal lesions in triple-transgenic mouse hippocampus.
Lauritzen I, Pardossi-Piquard R, Bauer C, Brigham E, Abraham JD, Ranaldi S, Fraser P, St-George-Hyslop P, Le Thuc O, Espin V, Chami L, Dunys J, Checler F. Lauritzen I, et al. Among authors: bauer c. J Neurosci. 2012 Nov 14;32(46):16243-1655a. doi: 10.1523/JNEUROSCI.2775-12.2012. J Neurosci. 2012. PMID: 23152608 Free PMC article.
Study on Aβ34 biology and detection in transgenic mice brains.
Caillava C, Ranaldi S, Lauritzen I, Bauer C, Fareh J, Abraham JD, Checler F. Caillava C, et al. Among authors: bauer c. Neurobiol Aging. 2014 Jul;35(7):1570-81. doi: 10.1016/j.neurobiolaging.2014.01.011. Epub 2014 Jan 11. Neurobiol Aging. 2014. PMID: 24495834
MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease.
Baranger K, Marchalant Y, Bonnet AE, Crouzin N, Carrete A, Paumier JM, Py NA, Bernard A, Bauer C, Charrat E, Moschke K, Seiki M, Vignes M, Lichtenthaler SF, Checler F, Khrestchatisky M, Rivera S. Baranger K, et al. Among authors: bauer c. Cell Mol Life Sci. 2016 Jan;73(1):217-36. doi: 10.1007/s00018-015-1992-1. Epub 2015 Jul 23. Cell Mol Life Sci. 2016. PMID: 26202697 Free PMC article.
2,483 results