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Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR. Lacampagne A, et al. Acta Neuropathol. 2017 Nov;134(5):749-767. doi: 10.1007/s00401-017-1733-7. Epub 2017 Jun 19. Acta Neuropathol. 2017. PMID: 28631094 Free article.
PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure.
Reiken S, Lacampagne A, Zhou H, Kherani A, Lehnart SE, Ward C, Huang F, Gaburjakova M, Gaburjakova J, Rosemblit N, Warren MS, He KL, Yi GH, Wang J, Burkhoff D, Vassort G, Marks AR. Reiken S, et al. Among authors: lacampagne a. J Cell Biol. 2003 Mar 17;160(6):919-28. doi: 10.1083/jcb.200211012. Epub 2003 Mar 10. J Cell Biol. 2003. PMID: 12629052 Free PMC article.
Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity.
Bellinger AM, Reiken S, Dura M, Murphy PW, Deng SX, Landry DW, Nieman D, Lehnart SE, Samaru M, LaCampagne A, Marks AR. Bellinger AM, et al. Among authors: lacampagne a. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2198-202. doi: 10.1073/pnas.0711074105. Epub 2008 Feb 11. Proc Natl Acad Sci U S A. 2008. PMID: 18268335 Free PMC article.
[Ryanodine receptor and heart disease].
Lacampagne A, Fauconnier J, Richard S. Lacampagne A, et al. Med Sci (Paris). 2008 Apr;24(4):399-405. doi: 10.1051/medsci/2008244399. Med Sci (Paris). 2008. PMID: 18405639 Free article. Review. French.
Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy.
Fauconnier J, Thireau J, Reiken S, Cassan C, Richard S, Matecki S, Marks AR, Lacampagne A. Fauconnier J, et al. Among authors: lacampagne a. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1559-64. doi: 10.1073/pnas.0908540107. Epub 2010 Jan 4. Proc Natl Acad Sci U S A. 2010. PMID: 20080623 Free PMC article.
Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion.
Fauconnier J, Meli AC, Thireau J, Roberge S, Shan J, Sassi Y, Reiken SR, Rauzier JM, Marchand A, Chauvier D, Cassan C, Crozier C, Bideaux P, Lompré AM, Jacotot E, Marks AR, Lacampagne A. Fauconnier J, et al. Among authors: lacampagne a. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13258-63. doi: 10.1073/pnas.1100286108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788490 Free PMC article.
160 results