Zalk R - Search Results

1

Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.

Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, Shelanski ML, Checler F, Chami M, Marks AR. Lacampagne A, et al. Among authors: zalk r. Acta Neuropathol. 2017 Nov;134(5):749-767. doi: 10.1007/s00401-017-1733-7. Epub 2017 Jun 19. Acta Neuropathol. 2017. PMID: 28631094 Free article.

2

Modulation of the ryanodine receptor and intracellular calcium.

Zalk R, Lehnart SE, Marks AR. Zalk R, et al. Annu Rev Biochem. 2007;76:367-85. doi: 10.1146/annurev.biochem.76.053105.094237. Annu Rev Biochem. 2007. PMID: 17506640 Review.

3

Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.

Andersson DC, Betzenhauser MJ, Reiken S, Meli AC, Umanskaya A, Xie W, Shiomi T, Zalk R, Lacampagne A, Marks AR. Andersson DC, et al. Among authors: zalk r. Cell Metab. 2011 Aug 3;14(2):196-207. doi: 10.1016/j.cmet.2011.05.014. Cell Metab. 2011. PMID: 21803290 Free PMC article.

4

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

Bussiere R, Lacampagne A, Reiken S, Liu X, Scheuerman V, Zalk R, Martin C, Checler F, Marks AR, Chami M. Bussiere R, et al. Among authors: zalk r. J Biol Chem. 2017 Jun 16;292(24):10153-10168. doi: 10.1074/jbc.M116.743070. Epub 2017 May 5. J Biol Chem. 2017. PMID: 28476886 Free PMC article.

5

Ca²⁺ Release Channels Join the 'Resolution Revolution'.

Zalk R, Marks AR. Zalk R, et al. Trends Biochem Sci. 2017 Jul;42(7):543-555. doi: 10.1016/j.tibs.2017.04.005. Epub 2017 May 9. Trends Biochem Sci. 2017. PMID: 28499500 Free PMC article. Review.

6

RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation.

Yuan Q, Dridi H, Clarke OB, Reiken S, Melville Z, Wronska A, Kushnir A, Zalk R, Sittenfeld L, Marks AR. Yuan Q, et al. Among authors: zalk r. Acta Neuropathol Commun. 2021 Nov 22;9(1):186. doi: 10.1186/s40478-021-01287-3. Acta Neuropathol Commun. 2021. PMID: 34809703 Free PMC article.

7

Structure of a mammalian ryanodine receptor.

Zalk R, Clarke OB, des Georges A, Grassucci RA, Reiken S, Mancia F, Hendrickson WA, Frank J, Marks AR. Zalk R, et al. Nature. 2015 Jan 1;517(7532):44-9. doi: 10.1038/nature13950. Epub 2014 Dec 1. Nature. 2015. PMID: 25470061 Free PMC article.

8

Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target.

Dridi H, Kushnir A, Zalk R, Yuan Q, Melville Z, Marks AR. Dridi H, et al. Among authors: zalk r. Nat Rev Cardiol. 2020 Nov;17(11):732-747. doi: 10.1038/s41569-020-0394-8. Epub 2020 Jun 18. Nat Rev Cardiol. 2020. PMID: 32555383 Free PMC article. Review.

9

Reply to 'Mechanisms of ryanodine receptor 2 dysfunction in heart failure'.

Dridi H, Kushnir A, Zalk R, Yuan Q, Melville Z, Marks AR. Dridi H, et al. Among authors: zalk r. Nat Rev Cardiol. 2020 Nov;17(11):749-750. doi: 10.1038/s41569-020-00444-w. Nat Rev Cardiol. 2020. PMID: 32901149 No abstract available.

10

Structural Basis for Gating and Activation of RyR1.

des Georges A, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J. des Georges A, et al. Among authors: zalk r. Cell. 2016 Sep 22;167(1):145-157.e17. doi: 10.1016/j.cell.2016.08.075. Cell. 2016. PMID: 27662087 Free PMC article.

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