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Structural design and synthesis of arylalkynyl amide-type peroxisome proliferator-activated receptor γ (PPARγ)-selective antagonists based on the helix12-folding inhibition hypothesis.
Ohashi M, Gamo K, Tanaka Y, Waki M, Beniyama Y, Matsuno K, Wada J, Tenta M, Eguchi J, Makishima M, Matsuura N, Oyama T, Miyachi H. Ohashi M, et al. Among authors: beniyama y. Eur J Med Chem. 2015 Jan 27;90:53-67. doi: 10.1016/j.ejmech.2014.11.017. Epub 2014 Nov 7. Eur J Med Chem. 2015. PMID: 25461311