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Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm.
McGrail DJ, Lin CC, Garnett J, Liu Q, Mo W, Dai H, Lu Y, Yu Q, Ju Z, Yin J, Vellano CP, Hennessy B, Mills GB, Lin SY. McGrail DJ, et al. Among authors: lin sy, lin cc. NPJ Syst Biol Appl. 2017 Mar 6;3:8. doi: 10.1038/s41540-017-0011-6. eCollection 2017. NPJ Syst Biol Appl. 2017. PMID: 28649435 Free PMC article.
BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer.
Rai R, Dai H, Multani AS, Li K, Chin K, Gray J, Lahad JP, Liang J, Mills GB, Meric-Bernstam F, Lin SY. Rai R, et al. Among authors: lin sy. Cancer Cell. 2006 Aug;10(2):145-57. doi: 10.1016/j.ccr.2006.07.002. Epub 2006 Jul 27. Cancer Cell. 2006. PMID: 16872911 Free PMC article.
BRIT1/MCPH1 links chromatin remodelling to DNA damage response.
Peng G, Yim EK, Dai H, Jackson AP, Burgt Iv, Pan MR, Hu R, Li K, Lin SY. Peng G, et al. Among authors: lin sy. Nat Cell Biol. 2009 Jul;11(7):865-72. doi: 10.1038/ncb1895. Epub 2009 Jun 14. Nat Cell Biol. 2009. PMID: 19525936 Free PMC article.
Genome-wide transcriptome profiling of homologous recombination DNA repair.
Peng G, Chun-Jen Lin C, Mo W, Dai H, Park YY, Kim SM, Peng Y, Mo Q, Siwko S, Hu R, Lee JS, Hennessy B, Hanash S, Mills GB, Lin SY. Peng G, et al. Among authors: lin sy. Nat Commun. 2014;5:3361. doi: 10.1038/ncomms4361. Nat Commun. 2014. PMID: 24553445 Free PMC article.
2,935 results