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Switching on the activity of 1,5-diaryl-pyrrole derivatives against drug-resistant ESKAPE bacteria: Structure-activity relationships and mode of action studies.
Masci D, Hind C, Islam MK, Toscani A, Clifford M, Coluccia A, Conforti I, Touitou M, Memdouh S, Wei X, La Regina G, Silvestri R, Sutton JM, Castagnolo D. Masci D, et al. Among authors: clifford m. Eur J Med Chem. 2019 Sep 15;178:500-514. doi: 10.1016/j.ejmech.2019.05.087. Epub 2019 Jun 3. Eur J Med Chem. 2019. PMID: 31202995
Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy.
Fields FR, Manzo G, Hind CK, Janardhanan J, Foik IP, Carmo Silva PD, Balsara RD, Clifford M, Vu HM, Ross JN, Kalwajtys VR, Gonzalez AJ, Bui TT, Ploplis VA, Castellino FJ, Siryaporn A, Chang M, Sutton JM, Mason AJ, Lee S. Fields FR, et al. Among authors: clifford m. ACS Pharmacol Transl Sci. 2020 Feb 21;3(3):418-424. doi: 10.1021/acsptsci.0c00001. eCollection 2020 Jun 12. ACS Pharmacol Transl Sci. 2020. PMID: 32566907 Free PMC article.
A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy.
Manzo G, Hind CK, Ferguson PM, Amison RT, Hodgson-Casson AC, Ciazynska KA, Weller BJ, Clarke M, Lam C, Man RCH, Shaughnessy BGO, Clifford M, Bui TT, Drake AF, Atkinson RA, Lam JKW, Pitchford SC, Page CP, Phoenix DA, Lorenz CD, Sutton JM, Mason AJ. Manzo G, et al. Among authors: clifford m. Commun Biol. 2020 Nov 27;3(1):697. doi: 10.1038/s42003-020-01420-3. Commun Biol. 2020. PMID: 33247193 Free PMC article.
258 results