Kim T - Search Results

1

In silico-designed novel non-peptidic ABAD L_D hot spot mimetics reverse Aβ-induced mitochondrial impairments in vitro.

Viswanath ANI, Kim T, Jung SY, Lim SM, Pae AN. Viswanath ANI, et al. Among authors: kim t. Chem Biol Drug Des. 2017 Dec;90(6):1041-1055. doi: 10.1111/cbdd.13065. Epub 2017 Jul 27. Chem Biol Drug Des. 2017. PMID: 28660722

2

In silico probing and biological evaluation of SETDB1/ESET-targeted novel compounds that reduce tri-methylated histone H3K9 (H3K9me3) level.

Park I, Hwang YJ, Kim T, Viswanath ANI, Londhe AM, Jung SY, Sim KM, Min SJ, Lee JE, Seong J, Kim YK, No KT, Ryu H, Pae AN. Park I, et al. Among authors: kim yk, kim t. J Comput Aided Mol Des. 2017 Oct;31(10):877-889. doi: 10.1007/s10822-017-0052-3. Epub 2017 Sep 6. J Comput Aided Mol Des. 2017. PMID: 28879500

3

Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity.

Kim T, Son WS, Morshed MN, Londhe AM, Jung SY, Park JH, Park WK, Lim SM, Park KD, Cho SJ, Jeong KS, Lee J, Pae AN. Kim T, et al. Eur J Med Chem. 2017 Dec 1;141:240-256. doi: 10.1016/j.ejmech.2017.09.033. Epub 2017 Sep 21. Eur J Med Chem. 2017. PMID: 29031071

4

Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010 - 2015; part 2).

Kim T, Pae AN. Kim T, et al. Expert Opin Ther Pat. 2016 Nov;26(11):1353-1366. doi: 10.1080/13543776.2016.1230605. Epub 2016 Sep 16. Expert Opin Ther Pat. 2016. PMID: 27599163 Review.

5

Translocator protein (TSPO) ligands for the diagnosis or treatment of neurodegenerative diseases: a patent review (2010-2015; part 1).

Kim T, Pae AN. Kim T, et al. Expert Opin Ther Pat. 2016 Nov;26(11):1325-1351. doi: 10.1080/13543776.2016.1230606. Epub 2016 Sep 13. Expert Opin Ther Pat. 2016. PMID: 27607364 Review.

6

Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease.

Kim T, Yang HY, Park BG, Jung SY, Park JH, Park KD, Min SJ, Tae J, Yang H, Cho S, Cho SJ, Song H, Mook-Jung I, Lee J, Pae AN. Kim T, et al. Eur J Med Chem. 2017 Jan 5;125:1172-1192. doi: 10.1016/j.ejmech.2016.11.017. Epub 2016 Nov 9. Eur J Med Chem. 2017. PMID: 27855359

7

The translocator protein ligands as mitochondrial functional modulators for the potential anti-Alzheimer agents.

Kim T, Morshed MN, Londhe AM, Lim JW, Lee HE, Cho S, Cho SJ, Hwang H, Lim SM, Lee JY, Lee J, Pae AN. Kim T, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):831-846. doi: 10.1080/14756366.2021.1900158. J Enzyme Inhib Med Chem. 2021. PMID: 33752569 Free PMC article.

8

Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.

Kim T, Keum G, Pae AN. Kim T, et al. Expert Opin Ther Pat. 2013 Aug;23(8):919-43. doi: 10.1517/13543776.2013.780597. Epub 2013 May 4. Expert Opin Ther Pat. 2013. PMID: 23641970 Review.

9

Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR2) antagonists.

Cho NC, Cha JH, Kim H, Kwak J, Kim D, Seo SH, Shin JS, Kim T, Park KD, Lee J, No KT, Kim YK, Lee KT, Pae AN. Cho NC, et al. Among authors: kim h, kim yk, kim d, kim t. Bioorg Med Chem. 2015 Dec 15;23(24):7717-27. doi: 10.1016/j.bmc.2015.11.016. Epub 2015 Nov 18. Bioorg Med Chem. 2015. PMID: 26631441

10

Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: a potential treatment for neuropathic pain.

Cho GH, Kim T, Son WS, Seo SH, Min SJ, Cho YS, Keum G, Jeong KS, Koh HY, Lee J, Pae AN. Cho GH, et al. Among authors: kim t. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1324-8. doi: 10.1016/j.bmcl.2015.01.035. Epub 2015 Jan 24. Bioorg Med Chem Lett. 2015. PMID: 25677662

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