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Page 1
D-myo-inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation.
Trinquet E, Fink M, Bazin H, Grillet F, Maurin F, Bourrier E, Ansanay H, Leroy C, Michaud A, Durroux T, Maurel D, Malhaire F, Goudet C, Pin JP, Naval M, Hernout O, Chrétien F, Chapleur Y, Mathis G. Trinquet E, et al. Among authors: durroux t. Anal Biochem. 2006 Nov 1;358(1):126-35. doi: 10.1016/j.ab.2006.08.002. Epub 2006 Aug 30. Anal Biochem. 2006. PMID: 16965760
Time-resolved FRET between GPCR ligands reveals oligomers in native tissues.
Albizu L, Cottet M, Kralikova M, Stoev S, Seyer R, Brabet I, Roux T, Bazin H, Bourrier E, Lamarque L, Breton C, Rives ML, Newman A, Javitch J, Trinquet E, Manning M, Pin JP, Mouillac B, Durroux T. Albizu L, et al. Among authors: durroux t. Nat Chem Biol. 2010 Aug;6(8):587-94. doi: 10.1038/nchembio.396. Epub 2010 Jul 11. Nat Chem Biol. 2010. PMID: 20622858 Free PMC article.
A fluorescent ligand-binding alternative using Tag-lite® technology.
Zwier JM, Roux T, Cottet M, Durroux T, Douzon S, Bdioui S, Gregor N, Bourrier E, Oueslati N, Nicolas L, Tinel N, Boisseau C, Yverneau P, Charrier-Savournin F, Fink M, Trinquet E. Zwier JM, et al. Among authors: durroux t. J Biomol Screen. 2010 Dec;15(10):1248-59. doi: 10.1177/1087057110384611. Epub 2010 Oct 25. J Biomol Screen. 2010. PMID: 20974902
The oligomeric state sets GABA(B) receptor signalling efficacy.
Comps-Agrar L, Kniazeff J, Nørskov-Lauritsen L, Maurel D, Gassmann M, Gregor N, Prézeau L, Bettler B, Durroux T, Trinquet E, Pin JP. Comps-Agrar L, et al. Among authors: durroux t. EMBO J. 2011 May 6;30(12):2336-49. doi: 10.1038/emboj.2011.143. EMBO J. 2011. PMID: 21552208 Free PMC article.
Structural insights into biased G protein-coupled receptor signaling revealed by fluorescence spectroscopy.
Rahmeh R, Damian M, Cottet M, Orcel H, Mendre C, Durroux T, Sharma KS, Durand G, Pucci B, Trinquet E, Zwier JM, Deupi X, Bron P, Banères JL, Mouillac B, Granier S. Rahmeh R, et al. Among authors: durroux t. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6733-8. doi: 10.1073/pnas.1201093109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493271 Free PMC article.
73 results