Padegimas L - Search Results

1

Intracerebral injections of DNA nanoparticles encoding for a therapeutic gene provide partial neuroprotection in an animal model of neurodegeneration.

Yurek D, Hasselrot U, Sesenoglu-Laird O, Padegimas L, Cooper M. Yurek D, et al. Among authors: padegimas l. Nanomedicine. 2017 Oct;13(7):2209-2217. doi: 10.1016/j.nano.2017.06.010. Epub 2017 Jun 27. Nanomedicine. 2017. PMID: 28666950

2

Long-term transgene expression in the central nervous system using DNA nanoparticles.

Yurek DM, Fletcher AM, Smith GM, Seroogy KB, Ziady AG, Molter J, Kowalczyk TH, Padegimas L, Cooper MJ. Yurek DM, et al. Among authors: padegimas l. Mol Ther. 2009 Apr;17(4):641-50. doi: 10.1038/mt.2009.2. Epub 2009 Feb 17. Mol Ther. 2009. PMID: 19223866 Free PMC article.

3

Compacted DNA nanoparticle gene transfer of GDNF to the rat striatum enhances the survival of grafted fetal dopamine neurons.

Yurek DM, Flectcher AM, Kowalczyk TH, Padegimas L, Cooper MJ. Yurek DM, et al. Among authors: padegimas l. Cell Transplant. 2009;18(10):1183-96. doi: 10.3727/096368909X12483162196881. Epub 2009 Jun 22. Cell Transplant. 2009. PMID: 19650971 Free PMC article.

4

DNA nanoparticles: detection of long-term transgene activity in brain using bioluminescence imaging.

Yurek DM, Fletcher AM, McShane M, Kowalczyk TH, Padegimas L, Weatherspoon MR, Kaytor MD, Cooper MJ, Ziady AG. Yurek DM, et al. Among authors: padegimas l. Mol Imaging. 2011 Oct;10(5):327-39. doi: 10.2310/7290.2010.00053. Epub 2011 Apr 27. Mol Imaging. 2011. PMID: 21521549 Free PMC article.

5

Transgene expression in the striatum following intracerebral injections of DNA nanoparticles encoding for human glial cell line-derived neurotrophic factor.

Fletcher AM, Kowalczyk TH, Padegimas L, Cooper MJ, Yurek DM. Fletcher AM, et al. Among authors: padegimas l. Neuroscience. 2011 Oct 27;194:220-6. doi: 10.1016/j.neuroscience.2011.07.072. Epub 2011 Aug 4. Neuroscience. 2011. PMID: 21839809 Free PMC article.

6

Optimization of hCFTR lung expression in mice using DNA nanoparticles.

Padegimas L, Kowalczyk TH, Adams S, Gedeon CR, Oette SM, Dines K, Hyatt SL, Sesenoglu-Laird O, Tyr O, Moen RC, Cooper MJ. Padegimas L, et al. Mol Ther. 2012 Jan;20(1):63-72. doi: 10.1038/mt.2011.196. Epub 2011 Sep 27. Mol Ther. 2012. PMID: 21952168 Free PMC article.

7

Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain.

Harmon BT, Aly AE, Padegimas L, Sesenoglu-Laird O, Cooper MJ, Waszczak BL. Harmon BT, et al. Among authors: padegimas l. Gene Ther. 2014 May;21(5):514-21. doi: 10.1038/gt.2014.28. Epub 2014 Mar 27. Gene Ther. 2014. PMID: 24670994

8

Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles.

Yurek DM, Hasselrot U, Cass WA, Sesenoglu-Laird O, Padegimas L, Cooper MJ. Yurek DM, et al. Among authors: padegimas l. Neuroscience. 2015 Jan 22;284:500-512. doi: 10.1016/j.neuroscience.2014.10.026. Epub 2014 Oct 22. Neuroscience. 2015. PMID: 25453772 Free PMC article.

9

Optimizing Non-viral Gene Therapy Vectors for Delivery to Photoreceptors and Retinal Pigment Epithelial Cells.

Zulliger R, Watson JN, Al-Ubaidi MR, Padegimas L, Sesenoglu-Laird O, Cooper MJ, Naash MI. Zulliger R, et al. Among authors: padegimas l. Adv Exp Med Biol. 2018;1074:109-115. doi: 10.1007/978-3-319-75402-4_14. Adv Exp Med Biol. 2018. PMID: 29721934

10

Intranasal Delivery of pGDNF DNA Nanoparticles Provides Neuroprotection in the Rat 6-Hydroxydopamine Model of Parkinson's Disease.

Aly AE, Harmon BT, Padegimas L, Sesenoglu-Laird O, Cooper MJ, Waszczak BL. Aly AE, et al. Among authors: padegimas l. Mol Neurobiol. 2019 Jan;56(1):688-701. doi: 10.1007/s12035-018-1109-6. Epub 2018 May 19. Mol Neurobiol. 2019. PMID: 29779176

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