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Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons.
Almanzar G, Schwaiger S, Jenewein B, Keller M, Herndler-Brandstetter D, Würzner R, Schönitzer D, Grubeck-Loebenstein B. Almanzar G, et al. Among authors: keller m. J Virol. 2005 Mar;79(6):3675-83. doi: 10.1128/JVI.79.6.3675-3683.2005. J Virol. 2005. PMID: 15731261 Free PMC article.
Booster vaccination in the elderly: their success depends on the vaccine type applied earlier in life as well as on pre-vaccination antibody titers.
Kaml M, Weiskirchner I, Keller M, Luft T, Hoster E, Hasford J, Young L, Bartlett B, Neuner C, Fischer KH, Neuman B, Würzner R, Grubeck-Loebenstein B. Kaml M, et al. Among authors: keller m. Vaccine. 2006 Nov 17;24(47-48):6808-11. doi: 10.1016/j.vaccine.2006.06.037. Epub 2006 Jul 10. Vaccine. 2006. PMID: 16872725
Plasma cell numbers decrease in bone marrow of old patients.
Pritz T, Lair J, Ban M, Keller M, Weinberger B, Krismer M, Grubeck-Loebenstein B. Pritz T, et al. Among authors: keller m. Eur J Immunol. 2015 Mar;45(3):738-46. doi: 10.1002/eji.201444878. Epub 2014 Dec 23. Eur J Immunol. 2015. PMID: 25430805 Free article. Clinical Trial.
3,649 results