Nussbaum G - Search Results

1

Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway.

Litvak Y, Sharon S, Hyams M, Zhang L, Kobi S, Katsowich N, Dishon S, Nussbaum G, Dong N, Shao F, Rosenshine I. Litvak Y, et al. Among authors: nussbaum g. PLoS Pathog. 2017 Jul 3;13(7):e1006472. doi: 10.1371/journal.ppat.1006472. eCollection 2017 Jul. PLoS Pathog. 2017. PMID: 28671993 Free PMC article.

2

Porphyromonas gingivalis Promotes Unrestrained Type I Interferon Production by Dysregulating TAM Signaling via MYD88 Degradation.

Mizraji G, Nassar M, Segev H, Sharawi H, Eli-Berchoer L, Capucha T, Nir T, Tabib Y, Maimon A, Dishon S, Shapira L, Nussbaum G, Wilensky A, Hovav AH. Mizraji G, et al. Among authors: nussbaum g. Cell Rep. 2017 Jan 10;18(2):419-431. doi: 10.1016/j.celrep.2016.12.047. Cell Rep. 2017. PMID: 28076786 Free article.

3

Inhibition of Myeloid Differentiation Factor 88 Reduces Human and Mouse T-Cell Interleukin-17 and IFNγ Production and Ameliorates Experimental Autoimmune Encephalomyelitis Induced in Mice.

Dishon S, Cohen SJ, Cohen IR, Nussbaum G. Dishon S, et al. Among authors: nussbaum g. Front Immunol. 2017 May 29;8:615. doi: 10.3389/fimmu.2017.00615. eCollection 2017. Front Immunol. 2017. PMID: 28611775 Free PMC article.

4

Development of a Novel Backbone Cyclic Peptide Inhibitor of the Innate Immune TLR/IL1R Signaling Protein MyD88.

Dishon S, Schumacher A, Fanous J, Talhami A, Kassis I, Karussis D, Gilon C, Hoffman A, Nussbaum G. Dishon S, et al. Among authors: nussbaum g. Sci Rep. 2018 Jun 21;8(1):9476. doi: 10.1038/s41598-018-27773-8. Sci Rep. 2018. PMID: 29930295 Free PMC article.

5

Myristoylation Confers Oral Bioavailability and Improves the Bioactivity of c(MyD 4-4), a Cyclic Peptide Inhibitor of MyD88.

Dishon S, Schumacher-Klinger A, Gilon C, Hoffman A, Nussbaum G. Dishon S, et al. Among authors: nussbaum g. Mol Pharm. 2019 Apr 1;16(4):1516-1522. doi: 10.1021/acs.molpharmaceut.8b01180. Epub 2019 Mar 21. Mol Pharm. 2019. PMID: 30860380

6

How has neutrophil research improved our understanding of periodontal pathogenesis?

Nussbaum G, Shapira L. Nussbaum G, et al. J Clin Periodontol. 2011 Mar;38 Suppl 11:49-59. doi: 10.1111/j.1600-051X.2010.01678.x. J Clin Periodontol. 2011. PMID: 21323704 Review.

7

Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis.

Maekawa T, Krauss JL, Abe T, Jotwani R, Triantafilou M, Triantafilou K, Hashim A, Hoch S, Curtis MA, Nussbaum G, Lambris JD, Hajishengallis G. Maekawa T, et al. Among authors: nussbaum g. Cell Host Microbe. 2014 Jun 11;15(6):768-78. doi: 10.1016/j.chom.2014.05.012. Cell Host Microbe. 2014. PMID: 24922578 Free PMC article.

8

CX3CR1hi Monocyte/Macrophages Support Bacterial Survival and Experimental Infection-Driven Bone Resorption.

Steinmetz O, Hoch S, Avniel-Polak S, Gavish K, Eli-Berchoer L, Wilensky A, Nussbaum G. Steinmetz O, et al. Among authors: nussbaum g. J Infect Dis. 2016 May 1;213(9):1505-15. doi: 10.1093/infdis/jiv763. Epub 2015 Dec 23. J Infect Dis. 2016. PMID: 26704610

9

Porphyromonas gingivalis induction of TLR2 association with Vinculin enables PI3K activation and immune evasion.

Pandi K, Angabo S, Gnanasekaran J, Makkawi H, Eli-Berchoer L, Glaser F, Nussbaum G. Pandi K, et al. Among authors: nussbaum g. PLoS Pathog. 2023 Apr 6;19(4):e1011284. doi: 10.1371/journal.ppat.1011284. eCollection 2023 Apr. PLoS Pathog. 2023. PMID: 37023213 Free PMC article.

10

Cutting Edge: TLR2 is required for the innate response to Porphyromonas gingivalis: activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorption.

Burns E, Bachrach G, Shapira L, Nussbaum G. Burns E, et al. Among authors: nussbaum g. J Immunol. 2006 Dec 15;177(12):8296-300. doi: 10.4049/jimmunol.177.12.8296. J Immunol. 2006. PMID: 17142724

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