Iljina M - Search Results

1

Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species.

Iljina M, Hong L, Horrocks MH, Ludtmann MH, Choi ML, Hughes CD, Ruggeri FS, Guilliams T, Buell AK, Lee JE, Gandhi S, Lee SF, Bryant CE, Vendruscolo M, Knowles TPJ, Dobson CM, De Genst E, Klenerman D. Iljina M, et al. BMC Biol. 2017 Jul 3;15(1):57. doi: 10.1186/s12915-017-0390-6. BMC Biol. 2017. PMID: 28673288 Free PMC article.

2

Fast flow microfluidics and single-molecule fluorescence for the rapid characterization of α-synuclein oligomers.

Horrocks MH, Tosatto L, Dear AJ, Garcia GA, Iljina M, Cremades N, Dalla Serra M, Knowles TP, Dobson CM, Klenerman D. Horrocks MH, et al. Among authors: iljina m. Anal Chem. 2015 Sep 1;87(17):8818-26. doi: 10.1021/acs.analchem.5b01811. Epub 2015 Aug 14. Anal Chem. 2015. PMID: 26258431

3

Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids.

Horrocks MH, Lee SF, Gandhi S, Magdalinou NK, Chen SW, Devine MJ, Tosatto L, Kjaergaard M, Beckwith JS, Zetterberg H, Iljina M, Cremades N, Dobson CM, Wood NW, Klenerman D. Horrocks MH, et al. Among authors: iljina m. ACS Chem Neurosci. 2016 Mar 16;7(3):399-406. doi: 10.1021/acschemneuro.5b00324. Epub 2016 Feb 4. ACS Chem Neurosci. 2016. PMID: 26800462 Free PMC article.

4

Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading.

Iljina M, Garcia GA, Horrocks MH, Tosatto L, Choi ML, Ganzinger KA, Abramov AY, Gandhi S, Wood NW, Cremades N, Dobson CM, Knowles TP, Klenerman D. Iljina M, et al. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1206-15. doi: 10.1073/pnas.1524128113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884195 Free PMC article.

5

Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms.

Iljina M, Garcia GA, Dear AJ, Flint J, Narayan P, Michaels TC, Dobson CM, Frenkel D, Knowles TP, Klenerman D. Iljina M, et al. Sci Rep. 2016 Jun 27;6:28658. doi: 10.1038/srep28658. Sci Rep. 2016. PMID: 27346247 Free PMC article.

6

Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein.

Iljina M, Tosatto L, Choi ML, Sang JC, Ye Y, Hughes CD, Bryant CE, Gandhi S, Klenerman D. Iljina M, et al. Sci Rep. 2016 Sep 27;6:33928. doi: 10.1038/srep33928. Sci Rep. 2016. PMID: 27671749 Free PMC article.

7

Quantifying Co-Oligomer Formation by α-Synuclein.

Iljina M, Dear AJ, Garcia GA, De S, Tosatto L, Flagmeier P, Whiten DR, Michaels TCT, Frenkel D, Dobson CM, Knowles TPJ, Klenerman D. Iljina M, et al. ACS Nano. 2018 Nov 27;12(11):10855-10866. doi: 10.1021/acsnano.8b03575. Epub 2018 Oct 29. ACS Nano. 2018. PMID: 30371053 Free PMC article.

8

Entropic Inhibition: How the Activity of a AAA+ Machine Is Modulated by Its Substrate-Binding Domain.

Iljina M, Mazal H, Goloubinoff P, Riven I, Haran G. Iljina M, et al. ACS Chem Biol. 2021 Apr 16;16(4):775-785. doi: 10.1021/acschembio.1c00156. Epub 2021 Mar 19. ACS Chem Biol. 2021. PMID: 33739813 Free PMC article.

9

Time-resolved photoelectron imaging of excited state relaxation dynamics in phenol, catechol, resorcinol, and hydroquinone.

Livingstone RA, Thompson JO, Iljina M, Donaldson RJ, Sussman BJ, Paterson MJ, Townsend D. Livingstone RA, et al. Among authors: iljina m. J Chem Phys. 2012 Nov 14;137(18):184304. doi: 10.1063/1.4765104. J Chem Phys. 2012. PMID: 23163368

10

Tunable microsecond dynamics of an allosteric switch regulate the activity of a AAA+ disaggregation machine.

Mazal H, Iljina M, Barak Y, Elad N, Rosenzweig R, Goloubinoff P, Riven I, Haran G. Mazal H, et al. Among authors: iljina m. Nat Commun. 2019 Mar 29;10(1):1438. doi: 10.1038/s41467-019-09474-6. Nat Commun. 2019. PMID: 30926805 Free PMC article.

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