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Page 1
Functional consequences of the first reported mutations of the proto-oncogene PTTG1IP/PBF.
Imruetaicharoenchoke W, Fletcher A, Lu W, Watkins RJ, Modasia B, Poole VL, Nieto HR, Thompson RJ, Boelaert K, Read ML, Smith VE, McCabe CJ. Imruetaicharoenchoke W, et al. Among authors: modasia b. Endocr Relat Cancer. 2017 Sep;24(9):459-474. doi: 10.1530/ERC-16-0340. Epub 2017 Jul 4. Endocr Relat Cancer. 2017. PMID: 28676500 Free PMC article.
Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer.
Read ML, Fong JC, Modasia B, Fletcher A, Imruetaicharoenchoke W, Thompson RJ, Nieto H, Reynolds JJ, Bacon A, Mallick U, Hackshaw A, Watkinson JC, Boelaert K, Turnell AS, Smith VE, McCabe CJ. Read ML, et al. Among authors: modasia b. Oncogene. 2017 Sep 14;36(37):5296-5308. doi: 10.1038/onc.2017.154. Epub 2017 May 15. Oncogene. 2017. PMID: 28504713 Free PMC article.
The PTTG1-binding factor (PBF/PTTG1IP) regulates p53 activity in thyroid cells.
Read ML, Seed RI, Fong JC, Modasia B, Ryan GA, Watkins RJ, Gagliano T, Smith VE, Stratford AL, Kwan PK, Sharma N, Dixon OM, Watkinson JC, Boelaert K, Franklyn JA, Turnell AS, McCabe CJ. Read ML, et al. Among authors: modasia b. Endocrinology. 2014 Apr;155(4):1222-34. doi: 10.1210/en.2013-1646. Epub 2014 Feb 7. Endocrinology. 2014. PMID: 24506068 Free PMC article.
Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth.
Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE. Han A, et al. Among authors: modasia b. Cancers (Basel). 2023 Jun 30;15(13):3451. doi: 10.3390/cancers15133451. Cancers (Basel). 2023. PMID: 37444561 Free PMC article.