Alessi DR - Search Results

1

Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia.

Wang L, Fan J, Francis JM, Georghiou G, Hergert S, Li S, Gambe R, Zhou CW, Yang C, Xiao S, Cin PD, Bowden M, Kotliar D, Shukla SA, Brown JR, Neuberg D, Alessi DR, Zhang CZ, Kharchenko PV, Livak KJ, Wu CJ. Wang L, et al. Among authors: alessi dr. Genome Res. 2017 Aug;27(8):1300-1311. doi: 10.1101/gr.217331.116. Epub 2017 Jul 5. Genome Res. 2017. PMID: 28679620 Free PMC article.

2

Cancer, oncogenes and signal transduction.

McManus EJ, Alessi DR. McManus EJ, et al. Among authors: alessi dr. Genome Biol. 2004;5(7):332. doi: 10.1186/gb-2004-5-7-332. Epub 2004 Jun 24. Genome Biol. 2004. PMID: 15239827 Free PMC article.

3

Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice.

Bayascas JR, Leslie NR, Parsons R, Fleming S, Alessi DR. Bayascas JR, et al. Among authors: alessi dr. Curr Biol. 2005 Oct 25;15(20):1839-46. doi: 10.1016/j.cub.2005.08.066. Curr Biol. 2005. PMID: 16243031 Free article.

4

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors.

Sommer EM, Dry H, Cross D, Guichard S, Davies BR, Alessi DR. Sommer EM, et al. Among authors: alessi dr. Biochem J. 2013 Jun 15;452(3):499-508. doi: 10.1042/BJ20130342. Biochem J. 2013. PMID: 23581296 Free PMC article.

5

TSC1-TSC2: a complex tale of PKB-mediated S6K regulation.

McManus EJ, Alessi DR. McManus EJ, et al. Among authors: alessi dr. Nat Cell Biol. 2002 Sep;4(9):E214-6. doi: 10.1038/ncb0902-e214. Nat Cell Biol. 2002. PMID: 12205484 No abstract available.

6

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG. Hawley SA, et al. Among authors: alessi dr. J Biol. 2003;2(4):28. doi: 10.1186/1475-4924-2-28. Epub 2003 Sep 24. J Biol. 2003. PMID: 14511394 Free PMC article.

7

The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation.

McManus EJ, Collins BJ, Ashby PR, Prescott AR, Murray-Tait V, Armit LJ, Arthur JS, Alessi DR. McManus EJ, et al. Among authors: alessi dr. EMBO J. 2004 May 19;23(10):2071-82. doi: 10.1038/sj.emboj.7600218. Epub 2004 Apr 29. EMBO J. 2004. PMID: 15116068 Free PMC article.

8

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis.

McManus EJ, Sakamoto K, Armit LJ, Ronaldson L, Shpiro N, Marquez R, Alessi DR. McManus EJ, et al. Among authors: alessi dr. EMBO J. 2005 Apr 20;24(8):1571-83. doi: 10.1038/sj.emboj.7600633. Epub 2005 Mar 24. EMBO J. 2005. PMID: 15791206 Free PMC article.

9

Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart.

Mora A, Sakamoto K, McManus EJ, Alessi DR. Mora A, et al. Among authors: alessi dr. FEBS Lett. 2005 Jul 4;579(17):3632-8. doi: 10.1016/j.febslet.2005.05.040. FEBS Lett. 2005. Retraction in: FEBS Lett. 2024 Dec;598(23):2939. doi: 10.1002/1873-3468.15044 PMID: 15961082 Free article. Retracted.

10

Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3.

Lipina C, Huang X, Finlay D, McManus EJ, Alessi DR, Sutherland C. Lipina C, et al. Among authors: alessi dr. Biochem J. 2005 Dec 15;392(Pt 3):633-9. doi: 10.1042/BJ20051046. Biochem J. 2005. PMID: 16176184 Free PMC article.

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