Grandér D - Search Results

1

RNAi prodrugs targeting Plk1 induce specific gene silencing in primary cells from pediatric T-acute lymphoblastic leukemia patients.

Kolosenko I, Edsbäcker E, Björklund AC, Hamil AS, Goroshchuk O, Grandér D, Dowdy SF, Palm-Apergi C. Kolosenko I, et al. Among authors: grander d. J Control Release. 2017 Sep 10;261:199-206. doi: 10.1016/j.jconrel.2017.07.002. Epub 2017 Jul 3. J Control Release. 2017. PMID: 28684168

2

An activated JAK/STAT3 pathway and CD45 expression are associated with sensitivity to Hsp90 inhibitors in multiple myeloma.

Lin H, Kolosenko I, Björklund AC, Protsyuk D, Österborg A, Grandér D, Tamm KP. Lin H, et al. Among authors: grander d. Exp Cell Res. 2013 Mar 10;319(5):600-11. doi: 10.1016/j.yexcr.2012.12.006. Epub 2012 Dec 13. Exp Cell Res. 2013. PMID: 23246572

3

Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment.

Dyczynski M, Vesterlund M, Björklund AC, Zachariadis V, Janssen J, Gallart-Ayala H, Daskalaki E, Wheelock CE, Lehtiö J, Grandér D, Tamm KP, Nilsson R. Dyczynski M, et al. Among authors: grander d. Cell Death Dis. 2018 Aug 28;9(9):846. doi: 10.1038/s41419-018-0625-7. Cell Death Dis. 2018. PMID: 30154400 Free PMC article.

4

Silencing of CEBPB-AS1 modulates CEBPB expression and resensitizes BRAF-inhibitor resistant melanoma cells to vemurafenib.

Vidarsdottir L, Fernandes RV, Zachariadis V, Das I, Edsbäcker E, Sigvaldadottir I, Azimi A, Höiom V, Hansson J, Grandér D, Egyházi Brage S, Pokrovskaja Tamm K. Vidarsdottir L, et al. Among authors: grander d. Melanoma Res. 2020 Oct;30(5):443-454. doi: 10.1097/CMR.0000000000000675. Melanoma Res. 2020. PMID: 32467529 Free PMC article.

5

Identification of novel small molecules that inhibit STAT3-dependent transcription and function.

Kolosenko I, Yu Y, Busker S, Dyczynski M, Liu J, Haraldsson M, Palm Apergi C, Helleday T, Tamm KP, Page BDG, Grander D. Kolosenko I, et al. Among authors: grander d. PLoS One. 2017 Jun 21;12(6):e0178844. doi: 10.1371/journal.pone.0178844. eCollection 2017. PLoS One. 2017. PMID: 28636670 Free PMC article.

6

Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis.

Panaretakis T, Laane E, Pokrovskaja K, Björklund AC, Moustakas A, Zhivotovsky B, Heyman M, Shoshan MC, Grandér D. Panaretakis T, et al. Among authors: grander d. Mol Biol Cell. 2005 Aug;16(8):3821-31. doi: 10.1091/mbc.e04-10-0862. Epub 2005 May 25. Mol Biol Cell. 2005. PMID: 15917298 Free PMC article.

7

Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin.

Panaretakis T, Hjortsberg L, Tamm KP, Björklund AC, Joseph B, Grandér D. Panaretakis T, et al. Among authors: grander d. Mol Biol Cell. 2008 Jan;19(1):41-50. doi: 10.1091/mbc.e07-04-0358. Epub 2007 Oct 17. Mol Biol Cell. 2008. PMID: 17942603 Free PMC article.

8

Activation of STAT1 is required for interferon-alpha-mediated cell death.

Arulampalam V, Kolosenko I, Hjortsberg L, Björklund AC, Grandér D, Tamm KP. Arulampalam V, et al. Among authors: grander d. Exp Cell Res. 2011 Jan 1;317(1):9-19. doi: 10.1016/j.yexcr.2010.10.002. Epub 2010 Oct 16. Exp Cell Res. 2011. PMID: 20937272

9

Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs.

Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey-Bates EG, Edsbäcker E, Pellegrini P, Rassoolzadeh H, Brnjic S, Larsson R, Stark GR, Grandér D, Linder S, Tamm KP, De Milito A. Kolosenko I, et al. Among authors: grander d. Int J Cancer. 2015 Feb 15;136(4):E51-61. doi: 10.1002/ijc.29161. Epub 2014 Sep 4. Int J Cancer. 2015. PMID: 25156627

10

Sorafenib-induced defective autophagy promotes cell death by necroptosis.

Kharaziha P, Chioureas D, Baltatzis G, Fonseca P, Rodriguez P, Gogvadze V, Lennartsson L, Björklund AC, Zhivotovsky B, Grandér D, Egevad L, Nilsson S, Panaretakis T. Kharaziha P, et al. Among authors: grander d. Oncotarget. 2015 Nov 10;6(35):37066-82. doi: 10.18632/oncotarget.5797. Oncotarget. 2015. PMID: 26416459 Free PMC article.

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