Liu X - Search Results

1

Characterization of non-heme iron aliphatic halogenase WelO5* fromHapalosiphon welwitschiiIC-52-3: Identification of a minimal protein sequence motif that confers enzymatic chlorination specificity in the biosynthesis of welwitindolelinones.

Zhu Q, Liu X. Zhu Q, et al. Among authors: liu x. Beilstein J Org Chem. 2017 Jun 16;13:1168-1173. doi: 10.3762/bjoc.13.115. eCollection 2017. Beilstein J Org Chem. 2017. PMID: 28684995 Free PMC article.

2

Aliphatic Halogenase Enables Late-Stage C-H Functionalization: Selective Synthesis of a Brominated Fischerindole Alkaloid with Enhanced Antibacterial Activity.

Zhu Q, Hillwig ML, Doi Y, Liu X. Zhu Q, et al. Among authors: liu x. Chembiochem. 2016 Mar 15;17(6):466-70. doi: 10.1002/cbic.201500674. Epub 2016 Feb 4. Chembiochem. 2016. PMID: 26749394

3

Discovery of a Promiscuous Non-Heme Iron Halogenase in Ambiguine Alkaloid Biogenesis: Implication for an Evolvable Enzyme Family for Late-Stage Halogenation of Aliphatic Carbons in Small Molecules.

Hillwig ML, Zhu Q, Ittiamornkul K, Liu X. Hillwig ML, et al. Among authors: liu x. Angew Chem Int Ed Engl. 2016 May 4;55(19):5780-4. doi: 10.1002/anie.201601447. Epub 2016 Mar 30. Angew Chem Int Ed Engl. 2016. PMID: 27027281

4

Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5.

Mitchell AJ, Zhu Q, Maggiolo AO, Ananth NR, Hillwig ML, Liu X, Boal AK. Mitchell AJ, et al. Among authors: liu x. Nat Chem Biol. 2016 Aug;12(8):636-40. doi: 10.1038/nchembio.2112. Epub 2016 Jun 27. Nat Chem Biol. 2016. PMID: 27348090 Free PMC article.

5

Structure-Guided Reprogramming of a Hydroxylase To Halogenate Its Small Molecule Substrate.

Mitchell AJ, Dunham NP, Bergman JA, Wang B, Zhu Q, Chang WC, Liu X, Boal AK. Mitchell AJ, et al. Among authors: liu x. Biochemistry. 2017 Jan 24;56(3):441-444. doi: 10.1021/acs.biochem.6b01173. Epub 2017 Jan 11. Biochemistry. 2017. PMID: 28029241 Free PMC article.

6

In Vitro Stepwise Reconstitution of Amino Acid Derived Vinyl Isocyanide Biosynthesis: Detection of an Elusive Intermediate.

Chang WC, Sanyal D, Huang JL, Ittiamornkul K, Zhu Q, Liu X. Chang WC, et al. Among authors: liu x. Org Lett. 2017 Mar 3;19(5):1208-1211. doi: 10.1021/acs.orglett.7b00258. Epub 2017 Feb 17. Org Lett. 2017. PMID: 28212039

7

Molecular and genetic basis for early stage structural diversifications in hapalindole-type alkaloid biogenesis.

Zhu Q, Liu X. Zhu Q, et al. Among authors: liu x. Chem Commun (Camb). 2017 Mar 2;53(19):2826-2829. doi: 10.1039/c7cc00782e. Chem Commun (Camb). 2017. PMID: 28225144

8

Discovery of a Calcium-Dependent Enzymatic Cascade for the Selective Assembly of Hapalindole-Type Alkaloids: On the Biosynthetic Origin of Hapalindole U.

Zhu Q, Liu X. Zhu Q, et al. Among authors: liu x. Angew Chem Int Ed Engl. 2017 Jul 24;56(31):9062-9066. doi: 10.1002/anie.201703932. Epub 2017 Jun 29. Angew Chem Int Ed Engl. 2017. PMID: 28626997

9

Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.

Wong CP, Awakawa T, Nakashima Y, Mori T, Zhu Q, Liu X, Abe I. Wong CP, et al. Among authors: liu x. Angew Chem Int Ed Engl. 2018 Jan 8;57(2):560-563. doi: 10.1002/anie.201710682. Epub 2017 Dec 15. Angew Chem Int Ed Engl. 2018. PMID: 29178634

10

Biosynthesis of ambiguine indole alkaloids in cyanobacterium Fischerella ambigua.

Hillwig ML, Zhu Q, Liu X. Hillwig ML, et al. Among authors: liu x. ACS Chem Biol. 2014 Feb 21;9(2):372-7. doi: 10.1021/cb400681n. Epub 2013 Nov 20. ACS Chem Biol. 2014. PMID: 24180436

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