Huang W - Search Results

1

Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.

Li Z, Liu C, Xu X, Qiu Q, Su X, Dai Y, Yang J, Li H, Shi W, Liao C, Pan M, Huang W, Qian H. Li Z, et al. Among authors: huang w. Eur J Med Chem. 2017 Sep 29;138:458-479. doi: 10.1016/j.ejmech.2017.07.001. Epub 2017 Jul 3. Eur J Med Chem. 2017. PMID: 28689096

2

The first pharmacophore model for potent G protein-coupled receptor 119 agonist.

Zhu X, Huang D, Lan X, Tang C, Zhu Y, Han J, Huang W, Qian H. Zhu X, et al. Among authors: huang d, huang w. Eur J Med Chem. 2011 Jul;46(7):2901-7. doi: 10.1016/j.ejmech.2011.04.014. Epub 2011 Apr 13. Eur J Med Chem. 2011. PMID: 21524831

3

Design, synthesis, and biological activity of novel dicoumarol glucagon-like peptide 1 conjugates.

Han J, Sun L, Chu Y, Li Z, Huang D, Zhu X, Qian H, Huang W. Han J, et al. Among authors: huang d, huang w. J Med Chem. 2013 Dec 27;56(24):9955-68. doi: 10.1021/jm4017448. Epub 2013 Dec 13. J Med Chem. 2013. PMID: 24308627

4

Design, synthesis and biological evaluation of novel peptide MC62 analogues as potential antihyperglycemic agents.

Yang B, Mei Y, Wang X, Deng X, Qian H, Huang W. Yang B, et al. Among authors: huang w. Eur J Med Chem. 2014 Feb 12;73:105-11. doi: 10.1016/j.ejmech.2013.11.043. Epub 2013 Dec 12. Eur J Med Chem. 2014. PMID: 24384551

5

Design, synthesis and biological evaluation of novel peptides with anti-cancer and drug resistance-reversing activities.

Deng X, Qiu Q, Yang B, Wang X, Huang W, Qian H. Deng X, et al. Among authors: huang w. Eur J Med Chem. 2015 Jan 7;89:540-8. doi: 10.1016/j.ejmech.2014.10.072. Epub 2014 Oct 28. Eur J Med Chem. 2015. PMID: 25462264

6

Synthesis and biological evaluation of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists.

Wang X, Zhao T, Yang B, Li Z, Cui J, Dai Y, Qiu Q, Qiang H, Huang W, Qian H. Wang X, et al. Among authors: huang w. Bioorg Med Chem. 2015 Jan 1;23(1):132-40. doi: 10.1016/j.bmc.2014.11.016. Epub 2014 Nov 20. Bioorg Med Chem. 2015. PMID: 25481394

7

Design, Synthesis and in vivo Evaluation of Novel C-Aryl Glucosides as Potent Sodium-Dependent Glucose Cotransporters Inhibitors for the Treatment of Diabetes.

Li Z, Wang X, Xu X, Qiu Q, Jiao L, Huang W, Qian H. Li Z, et al. Among authors: huang w. Chem Biol Drug Des. 2015 Oct;86(4):764-75. doi: 10.1111/cbdd.12547. Epub 2015 Mar 20. Chem Biol Drug Des. 2015. PMID: 25732240

8

Design, synthesis and structure-activity relationship studies of novel phenoxyacetamide-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.

Li Z, Wang X, Xu X, Yang J, Qiu Q, Qiang H, Huang W, Qian H. Li Z, et al. Among authors: huang w. Bioorg Med Chem. 2015 Oct 15;23(20):6666-72. doi: 10.1016/j.bmc.2015.09.010. Epub 2015 Sep 5. Bioorg Med Chem. 2015. PMID: 26420383

9

Design, synthesis and biological activity of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists.

Li Z, Wang X, Xu X, Yang J, Xia W, Zhou X, Huang W, Qian H. Li Z, et al. Among authors: huang w. Bioorg Med Chem. 2015 Nov 15;23(22):7158-64. doi: 10.1016/j.bmc.2015.10.011. Epub 2015 Oct 8. Bioorg Med Chem. 2015. PMID: 26482570

10

Design, synthesis and Structure-activity relationship studies of new thiazole-based free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.

Li Z, Qiu Q, Xu X, Wang X, Jiao L, Su X, Pan M, Huang W, Qian H. Li Z, et al. Among authors: huang w. Eur J Med Chem. 2016 May 4;113:246-57. doi: 10.1016/j.ejmech.2016.02.040. Epub 2016 Feb 21. Eur J Med Chem. 2016. PMID: 26945112

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