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Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity.
Hu S, Leblanc AF, Gibson AA, Hong KW, Kim JY, Janke LJ, Li L, Vasilyeva A, Finkelstein DB, Sprowl JA, Sweet DH, Schlatter E, Ciarimboli G, Schellens J, Baker SD, Pabla N, Sparreboom A. Hu S, et al. Among authors: janke lj. Clin Transl Sci. 2017 Sep;10(5):412-420. doi: 10.1111/cts.12480. Epub 2017 Jul 8. Clin Transl Sci. 2017. PMID: 28689374 Free PMC article.
Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2.
Sprowl JA, Ciarimboli G, Lancaster CS, Giovinazzo H, Gibson AA, Du G, Janke LJ, Cavaletti G, Shields AF, Sparreboom A. Sprowl JA, et al. Among authors: janke lj. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11199-204. doi: 10.1073/pnas.1305321110. Epub 2013 Jun 17. Proc Natl Acad Sci U S A. 2013. PMID: 23776246 Free PMC article.
Cisplatin-induced renal injury is independently mediated by OCT2 and p53.
Sprowl JA, Lancaster CS, Pabla N, Hermann E, Kosloske AM, Gibson AA, Li L, Zeeh D, Schlatter E, Janke LJ, Ciarimboli G, Sparreboom A. Sprowl JA, et al. Among authors: janke lj. Clin Cancer Res. 2014 Aug 1;20(15):4026-35. doi: 10.1158/1078-0432.CCR-14-0319. Epub 2014 Jun 10. Clin Cancer Res. 2014. PMID: 24916697 Free PMC article.
Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine.
Diouf B, Wing C, Panetta JC, Eddins D, Lin W, Yang W, Fan Y, Pei D, Cheng C, Delaney SM, Zhang W, Bonten EJ, Crews KR, Paugh SW, Li L, Freeman BB 3rd, Autry RJ, Beard JA, Ferguson DC, Janke LJ, Ness KK, Chen T, Zakharenko SS, Jeha S, Pui CH, Relling MV, Eileen Dolan M, Evans WE. Diouf B, et al. Among authors: janke lj. Clin Transl Sci. 2021 Jul;14(4):1490-1504. doi: 10.1111/cts.13012. Epub 2021 May 31. Clin Transl Sci. 2021. PMID: 33742760 Free PMC article.
79 results