Wilson IA - Search Results

1

Structure-based optimization and synthesis of antiviral drug Arbidol analogues with significantly improved affinity to influenza hemagglutinin.

Wright ZVF, Wu NC, Kadam RU, Wilson IA, Wolan DW. Wright ZVF, et al. Among authors: wilson ia. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3744-3748. doi: 10.1016/j.bmcl.2017.06.074. Epub 2017 Jun 28. Bioorg Med Chem Lett. 2017. PMID: 28689973 Free PMC article.

2

Preliminary crystallographic data, primary sequence, and binding data for an anti-peptide Fab and its complex with a synthetic peptide from influenza virus hemagglutinin.

Schulze-Gahmen U, Rini JM, Arevalo J, Stura EA, Kenten JH, Wilson IA. Schulze-Gahmen U, et al. Among authors: wilson ia. J Biol Chem. 1988 Nov 15;263(32):17100-5. J Biol Chem. 1988. PMID: 3182835 Free article.

3

Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A.

Wolan DW, Teyton L, Rudolph MG, Villmow B, Bauer S, Busch DH, Wilson IA. Wolan DW, et al. Among authors: wilson ia. Nat Immunol. 2001 Mar;2(3):248-54. doi: 10.1038/85311. Nat Immunol. 2001. PMID: 11224525

4

10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.

Marsilje TH, Labroli MA, Hedrick MP, Jin Q, Desharnais J, Baker SJ, Gooljarsingh LT, Ramcharan J, Tavassoli A, Zhang Y, Wilson IA, Beardsley GP, Benkovic SJ, Boger DL. Marsilje TH, et al. Among authors: wilson ia. Bioorg Med Chem. 2002 Aug;10(8):2739-49. doi: 10.1016/s0968-0896(02)00102-5. Bioorg Med Chem. 2002. PMID: 12057663

5

Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase.

DeSantis G, Liu J, Clark DP, Heine A, Wilson IA, Wong CH. DeSantis G, et al. Among authors: wilson ia. Bioorg Med Chem. 2003 Jan 2;11(1):43-52. doi: 10.1016/s0968-0896(02)00429-7. Bioorg Med Chem. 2003. PMID: 12467706

6

Structural insights into the avian AICAR transformylase mechanism.

Wolan DW, Greasley SE, Beardsley GP, Wilson IA. Wolan DW, et al. Among authors: wilson ia. Biochemistry. 2002 Dec 31;41(52):15505-13. doi: 10.1021/bi020505x. Biochemistry. 2002. PMID: 12501179

7

Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.

Wolan DW, Greasley SE, Wall MJ, Benkovic SJ, Wilson IA. Wolan DW, et al. Among authors: wilson ia. Biochemistry. 2003 Sep 23;42(37):10904-14. doi: 10.1021/bi030106h. Biochemistry. 2003. PMID: 12974624

8

Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylase.

Marsilje TH, Hedrick MP, Desharnais J, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Marsilje TH, et al. Among authors: wilson ia. Bioorg Med Chem. 2003 Oct 1;11(20):4487-501. doi: 10.1016/s0968-0896(03)00456-5. Bioorg Med Chem. 2003. PMID: 13129585

9

10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylase.

Marsilje TH, Hedrick MP, Desharnais J, Capps K, Tavassoli A, Zhang Y, Wilson IA, Benkovic SJ, Boger DL. Marsilje TH, et al. Among authors: wilson ia. Bioorg Med Chem. 2003 Oct 1;11(20):4503-9. doi: 10.1016/s0968-0896(03)00457-7. Bioorg Med Chem. 2003. PMID: 13129586

10

Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.

Desharnais J, Hwang I, Zhang Y, Tavassoli A, Baboval J, Benkovic SJ, Wilson IA, Boger DL. Desharnais J, et al. Among authors: wilson ia. Bioorg Med Chem. 2003 Oct 1;11(20):4511-21. doi: 10.1016/s0968-0896(03)00458-9. Bioorg Med Chem. 2003. PMID: 13129587

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