Bussemaker HJ - Search Results

1

Network-based approaches that exploit inferred transcription factor activity to analyze the impact of genetic variation on gene expression.

Bussemaker HJ, Causton HC, Fazlollahi M, Lee E, Muroff I. Bussemaker HJ, et al. Curr Opin Syst Biol. 2017 Apr;2:98-102. doi: 10.1016/j.coisb.2017.04.002. Epub 2017 Apr 17. Curr Opin Syst Biol. 2017. PMID: 28691107 Free PMC article.

2

Identifying the genetic determinants of transcription factor activity.

Lee E, Bussemaker HJ. Lee E, et al. Among authors: bussemaker hj. Mol Syst Biol. 2010 Sep 21;6:412. doi: 10.1038/msb.2010.64. Mol Syst Biol. 2010. PMID: 20865005 Free PMC article.

3

Loss of subcellular lipid transport due to ARV1 deficiency disrupts organelle homeostasis and activates the unfolded protein response.

Shechtman CF, Henneberry AL, Seimon TA, Tinkelenberg AH, Wilcox LJ, Lee E, Fazlollahi M, Munkacsi AB, Bussemaker HJ, Tabas I, Sturley SL. Shechtman CF, et al. Among authors: bussemaker hj. J Biol Chem. 2011 Apr 8;286(14):11951-9. doi: 10.1074/jbc.M110.215038. Epub 2011 Jan 25. J Biol Chem. 2011. PMID: 21266578 Free PMC article.

4

Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis.

Lee E, de Ridder J, Kool J, Wessels LF, Bussemaker HJ. Lee E, et al. Among authors: bussemaker hj. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5747-52. doi: 10.1073/pnas.1309293111. Epub 2014 Apr 2. Proc Natl Acad Sci U S A. 2014. PMID: 24706889 Free PMC article.

5

Harnessing natural sequence variation to dissect posttranscriptional regulatory networks in yeast.

Fazlollahi M, Lee E, Muroff I, Lu XJ, Gomez-Alcala P, Causton HC, Bussemaker HJ. Fazlollahi M, et al. Among authors: bussemaker hj. G3 (Bethesda). 2014 Jun 17;4(8):1539-53. doi: 10.1534/g3.114.012039. G3 (Bethesda). 2014. PMID: 24938291 Free PMC article.

6

Identifying genetic modulators of the connectivity between transcription factors and their transcriptional targets.

Fazlollahi M, Muroff I, Lee E, Causton HC, Bussemaker HJ. Fazlollahi M, et al. Among authors: bussemaker hj. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1835-43. doi: 10.1073/pnas.1517140113. Epub 2016 Mar 10. Proc Natl Acad Sci U S A. 2016. PMID: 26966232 Free PMC article.

7

Identifying genetic regulatory variants that affect transcription factor activity.

Li X, Lappalainen T, Bussemaker HJ. Li X, et al. Among authors: bussemaker hj. Cell Genom. 2023 Aug 18;3(9):100382. doi: 10.1016/j.xgen.2023.100382. eCollection 2023 Sep 13. Cell Genom. 2023. PMID: 37719147 Free PMC article.

8

Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE.

Foat BC, Morozov AV, Bussemaker HJ. Foat BC, et al. Among authors: bussemaker hj. Bioinformatics. 2006 Jul 15;22(14):e141-9. doi: 10.1093/bioinformatics/btl223. Bioinformatics. 2006. PMID: 16873464

9

Quantitative modeling of transcription factor binding specificities using DNA shape.

Zhou T, Shen N, Yang L, Abe N, Horton J, Mann RS, Bussemaker HJ, Gordân R, Rohs R. Zhou T, et al. Among authors: bussemaker hj. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4654-9. doi: 10.1073/pnas.1422023112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775564 Free PMC article.

10

Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes.

Kribelbauer JF, Laptenko O, Chen S, Martini GD, Freed-Pastor WA, Prives C, Mann RS, Bussemaker HJ. Kribelbauer JF, et al. Among authors: bussemaker hj. Cell Rep. 2017 Jun 13;19(11):2383-2395. doi: 10.1016/j.celrep.2017.05.069. Cell Rep. 2017. PMID: 28614722 Free PMC article.

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