McDonald PC - Search Results

1

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

Swayampakula M, McDonald PC, Vallejo M, Coyaud E, Chafe SC, Westerback A, Venkateswaran G, Shankar J, Gao G, Laurent EMN, Lou Y, Bennewith KL, Supuran CT, Nabi IR, Raught B, Dedhar S. Swayampakula M, et al. Among authors: mcdonald pc. Oncogene. 2017 Nov 9;36(45):6244-6261. doi: 10.1038/onc.2017.219. Epub 2017 Jul 10. Oncogene. 2017. PMID: 28692057 Free PMC article.

2

Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival.

Troussard AA, McDonald PC, Wederell ED, Mawji NM, Filipenko NR, Gelmon KA, Kucab JE, Dunn SE, Emerman JT, Bally MB, Dedhar S. Troussard AA, et al. Among authors: mcdonald pc. Cancer Res. 2006 Jan 1;66(1):393-403. doi: 10.1158/0008-5472.CAN-05-2304. Cancer Res. 2006. PMID: 16397254 Free article.

3

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization.

Fielding AB, Dobreva I, McDonald PC, Foster LJ, Dedhar S. Fielding AB, et al. Among authors: mcdonald pc. J Cell Biol. 2008 Feb 25;180(4):681-9. doi: 10.1083/jcb.200710074. Epub 2008 Feb 18. J Cell Biol. 2008. PMID: 18283114 Free PMC article.

4

Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival.

McDonald PC, Oloumi A, Mills J, Dobreva I, Maidan M, Gray V, Wederell ED, Bally MB, Foster LJ, Dedhar S. McDonald PC, et al. Cancer Res. 2008 Mar 15;68(6):1618-24. doi: 10.1158/0008-5472.CAN-07-5869. Cancer Res. 2008. PMID: 18339839

5

Integrin-linked kinase regulates E-cadherin expression through PARP-1.

McPhee TR, McDonald PC, Oloumi A, Dedhar S. McPhee TR, et al. Among authors: mcdonald pc. Dev Dyn. 2008 Oct;237(10):2737-47. doi: 10.1002/dvdy.21685. Dev Dyn. 2008. PMID: 18773488 Free article.

6

Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis.

Lou Y, Preobrazhenska O, auf dem Keller U, Sutcliffe M, Barclay L, McDonald PC, Roskelley C, Overall CM, Dedhar S. Lou Y, et al. Among authors: mcdonald pc. Dev Dyn. 2008 Oct;237(10):2755-68. doi: 10.1002/dvdy.21658. Dev Dyn. 2008. PMID: 18773493 Free article.

7

Integrin-linked kinase--essential roles in physiology and cancer biology.

McDonald PC, Fielding AB, Dedhar S. McDonald PC, et al. J Cell Sci. 2008 Oct 1;121(Pt 19):3121-32. doi: 10.1242/jcs.017996. J Cell Sci. 2008. PMID: 18799788 Free article. Review.

8

Integrin-linked kinase: both Jekyll and Hyde in rhabdomyosarcoma.

McDonald PC, Dedhar S, Keller C. McDonald PC, et al. J Clin Invest. 2009 Jun;119(6):1452-5. doi: 10.1172/jci39457. J Clin Invest. 2009. PMID: 19504719 Free PMC article.

9

Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation.

Maydan M, McDonald PC, Sanghera J, Yan J, Rallis C, Pinchin S, Hannigan GE, Foster LJ, Ish-Horowicz D, Walsh MP, Dedhar S. Maydan M, et al. Among authors: mcdonald pc. PLoS One. 2010 Aug 23;5(8):e12356. doi: 10.1371/journal.pone.0012356. PLoS One. 2010. PMID: 20827300 Free PMC article.

10

Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.

Pacchiano F, Carta F, McDonald PC, Lou Y, Vullo D, Scozzafava A, Dedhar S, Supuran CT. Pacchiano F, et al. Among authors: mcdonald pc. J Med Chem. 2011 Mar 24;54(6):1896-902. doi: 10.1021/jm101541x. Epub 2011 Mar 1. J Med Chem. 2011. PMID: 21361354

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