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Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL.
Machuca-Parra AI, Bigger-Allen AA, Sanchez AV, Boutabla A, Cardona-Vélez J, Amarnani D, Saint-Geniez M, Siebel CW, Kim LA, D'Amore PA, Arboleda-Velasquez JF. Machuca-Parra AI, et al. J Exp Med. 2017 Aug 7;214(8):2271-2282. doi: 10.1084/jem.20161715. Epub 2017 Jul 11. J Exp Med. 2017. PMID: 28698285 Free PMC article.
CADASIL mutations impair Notch3 glycosylation by Fringe.
Arboleda-Velasquez JF, Rampal R, Fung E, Darland DC, Liu M, Martinez MC, Donahue CP, Navarro-Gonzalez MF, Libby P, D'Amore PA, Aikawa M, Haltiwanger RS, Kosik KS. Arboleda-Velasquez JF, et al. Hum Mol Genet. 2005 Jun 15;14(12):1631-9. doi: 10.1093/hmg/ddi171. Epub 2005 Apr 27. Hum Mol Genet. 2005. PMID: 15857853
Role of cell and matrix-bound VEGF isoforms in lens development.
Saint-Geniez M, Kurihara T, D'Amore PA. Saint-Geniez M, et al. Invest Ophthalmol Vis Sci. 2009 Jan;50(1):311-21. doi: 10.1167/iovs.08-2461. Epub 2008 Aug 29. Invest Ophthalmol Vis Sci. 2009. PMID: 18757513 Free PMC article.
228 results