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Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry.
Schweppe DK, Chavez JD, Lee CF, Caudal A, Kruse SE, Stuppard R, Marcinek DJ, Shadel GS, Tian R, Bruce JE. Schweppe DK, et al. Among authors: stuppard r. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1732-1737. doi: 10.1073/pnas.1617220114. Epub 2017 Jan 27. Proc Natl Acad Sci U S A. 2017. PMID: 28130547 Free PMC article.
Mitochondrial protein interaction landscape of SS-31.
Chavez JD, Tang X, Campbell MD, Reyes G, Kramer PA, Stuppard R, Keller A, Zhang H, Rabinovitch PS, Marcinek DJ, Bruce JE. Chavez JD, et al. Among authors: stuppard r. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15363-15373. doi: 10.1073/pnas.2002250117. Epub 2020 Jun 17. Proc Natl Acad Sci U S A. 2020. PMID: 32554501 Free PMC article.
Elamipretide Improves ADP Sensitivity in Aged Mitochondria by Increasing Uptake through the Adenine Nucleotide Translocator (ANT).
Pharaoh G, Kamat V, Kannan S, Stuppard RS, Whitson J, Martin-Perez M, Qian WJ, MacCoss MJ, Villen J, Rabinovitch P, Campbell MD, Sweet IR, Marcinek DJ. Pharaoh G, et al. Among authors: stuppard rs. bioRxiv [Preprint]. 2023 Feb 3:2023.02.01.525989. doi: 10.1101/2023.02.01.525989. bioRxiv. 2023. Update in: Geroscience. 2023 Dec;45(6):3529-3548. doi: 10.1007/s11357-023-00861-y PMID: 36778398 Free PMC article. Updated. Preprint.
The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT).
Pharaoh G, Kamat V, Kannan S, Stuppard RS, Whitson J, Martín-Pérez M, Qian WJ, MacCoss MJ, Villén J, Rabinovitch P, Campbell MD, Sweet IR, Marcinek DJ. Pharaoh G, et al. Among authors: stuppard rs. Geroscience. 2023 Dec;45(6):3529-3548. doi: 10.1007/s11357-023-00861-y. Epub 2023 Jul 18. Geroscience. 2023. PMID: 37462785 Free PMC article.
Inducible and reversible SOD2 knockdown in mouse skeletal muscle drives impaired pyruvate oxidation and reduced metabolic flexibility.
Ostrom EL, Stuppard R, Mattson-Hughes A, Marcinek DJ. Ostrom EL, et al. Among authors: stuppard r. bioRxiv [Preprint]. 2024 Sep 25:2024.09.23.614547. doi: 10.1101/2024.09.23.614547. bioRxiv. 2024. Update in: Free Radic Biol Med. 2025 Jan;226:237-250. doi: 10.1016/j.freeradbiomed.2024.10.310 PMID: 39386714 Free PMC article. Updated. Preprint.
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