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Page 1
Blocking TGF-β and β-Catenin Epithelial Crosstalk Exacerbates CKD.
Nlandu-Khodo S, Neelisetty S, Phillips M, Manolopoulou M, Bhave G, May L, Clark PE, Yang H, Fogo AB, Harris RC, Taketo MM, Lee E, Gewin LS. Nlandu-Khodo S, et al. Among authors: neelisetty s. J Am Soc Nephrol. 2017 Dec;28(12):3490-3503. doi: 10.1681/ASN.2016121351. Epub 2017 Jul 12. J Am Soc Nephrol. 2017. PMID: 28701516 Free PMC article.
Deleting the TGF-β receptor attenuates acute proximal tubule injury.
Gewin L, Vadivelu S, Neelisetty S, Srichai MB, Paueksakon P, Pozzi A, Harris RC, Zent R. Gewin L, et al. Among authors: neelisetty s. J Am Soc Nephrol. 2012 Dec;23(12):2001-11. doi: 10.1681/ASN.2012020139. Epub 2012 Nov 15. J Am Soc Nephrol. 2012. PMID: 23160515 Free PMC article.
Deleting the TGF-β receptor in proximal tubules impairs HGF signaling.
Nlandu Khodo S, Neelisetty S, Woodbury L, Green E, Harris RC, Zent R, Gewin L. Nlandu Khodo S, et al. Among authors: neelisetty s. Am J Physiol Renal Physiol. 2016 Mar 15;310(6):F499-510. doi: 10.1152/ajprenal.00446.2015. Epub 2016 Jan 6. Am J Physiol Renal Physiol. 2016. PMID: 26739889 Free PMC article.
Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease.
Nlandu-Khodo S, Osaki Y, Scarfe L, Yang H, Phillips-Mignemi M, Tonello J, Saito-Diaz K, Neelisetty S, Ivanova A, Huffstater T, McMahon R, Taketo MM, deCaestecker M, Kasinath B, Harris RC, Lee E, Gewin LS. Nlandu-Khodo S, et al. Among authors: neelisetty s. JCI Insight. 2020 May 21;5(10):e135454. doi: 10.1172/jci.insight.135454. JCI Insight. 2020. PMID: 32369448 Free PMC article.
Inactivation of Tsc2 in Abcg2 lineage-derived cells drives the appearance of polycystic lesions and fibrosis in the adult kidney.
Gewin LS, Summers ME, Harral JW, Gaskill CF, Khodo SN, Neelisetty S, Sullivan TM, Hopp K, Reese JJ, Klemm DJ, Kon V, Ess KC, Shi W, Majka SM. Gewin LS, et al. Among authors: neelisetty s. Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1201-F1210. doi: 10.1152/ajprenal.00629.2018. Epub 2019 Aug 28. Am J Physiol Renal Physiol. 2019. PMID: 31461347 Free PMC article.