Sun S - Search Results

1

LC/MS/MS Profiling of Tissue Oxysterols and its Application in Dextran Sodium Sulphate Induced Mouse Colitis Models.

Wu J, McDuffie JE, Song J, Harris MC, Raymond H, Chen Y, Nguyen L, Nguyen S, Kanerva J, McAllister HM, Deng X, Mani N, Liu C, Sun S. Wu J, et al. Among authors: sun s. Curr Top Med Chem. 2017;17(24):2781-2790. doi: 10.2174/1568026617666170713165519. Curr Top Med Chem. 2017. PMID: 28714418

2

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.

Thurmond RL, Desai PJ, Dunford PJ, Fung-Leung WP, Hofstra CL, Jiang W, Nguyen S, Riley JP, Sun S, Williams KN, Edwards JP, Karlsson L. Thurmond RL, et al. Among authors: sun s. J Pharmacol Exp Ther. 2004 Apr;309(1):404-13. doi: 10.1124/jpet.103.061754. Epub 2004 Jan 13. J Pharmacol Exp Ther. 2004. PMID: 14722321

3

Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: optimization of cellular potency.

Ameriks MK, Cai H, Edwards JP, Gebauer D, Gleason E, Gu Y, Karlsson L, Nguyen S, Sun S, Thurmond RL, Zhu J. Ameriks MK, et al. Among authors: sun s. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6135-9. doi: 10.1016/j.bmcl.2009.09.013. Epub 2009 Sep 10. Bioorg Med Chem Lett. 2009. PMID: 19783435

4

Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors: part 1.

Lee-Dutra A, Wiener DK, Arienti KL, Liu J, Mani N, Ameriks MK, Axe FU, Gebauer D, Desai PJ, Nguyen S, Randal M, Thurmond RL, Sun S, Karlsson L, Edwards JP, Jones TK, Grice CA. Lee-Dutra A, et al. Among authors: sun s. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2370-4. doi: 10.1016/j.bmcl.2010.01.108. Epub 2010 Jan 28. Bioorg Med Chem Lett. 2010. PMID: 20153648

5

Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors. Part 2: Modification of P3, P4, and P5 regions.

Wiener JJ, Wickboldt AT Jr, Wiener DK, Lee-Dutra A, Edwards JP, Karlsson L, Nguyen S, Sun S, Jones TK, Grice CA. Wiener JJ, et al. Among authors: sun s. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2375-8. doi: 10.1016/j.bmcl.2010.01.104. Epub 2010 Feb 1. Bioorg Med Chem Lett. 2010. PMID: 20171097

6

Thioether acetamides as P3 binding elements for tetrahydropyrido-pyrazole cathepsin S inhibitors.

Wiener DK, Lee-Dutra A, Bembenek S, Nguyen S, Thurmond RL, Sun S, Karlsson L, Grice CA, Jones TK, Edwards JP. Wiener DK, et al. Among authors: sun s. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2379-82. doi: 10.1016/j.bmcl.2010.01.103. Epub 2010 Feb 8. Bioorg Med Chem Lett. 2010. PMID: 20188543

7

Oxysterols direct B-cell migration through EBI2.

Liu C, Yang XV, Wu J, Kuei C, Mani NS, Zhang L, Yu J, Sutton SW, Qin N, Banie H, Karlsson L, Sun S, Lovenberg TW. Liu C, et al. Among authors: sun s. Nature. 2011 Jul 27;475(7357):519-23. doi: 10.1038/nature10226. Nature. 2011. PMID: 21796211

8

Identification of structural motifs critical for epstein-barr virus-induced molecule 2 function and homology modeling of the ligand docking site.

Zhang L, Shih AY, Yang XV, Kuei C, Wu J, Deng X, Mani NS, Mirzadegan T, Sun S, Lovenberg TW, Liu C. Zhang L, et al. Among authors: sun s. Mol Pharmacol. 2012 Dec;82(6):1094-103. doi: 10.1124/mol.112.080275. Epub 2012 Aug 28. Mol Pharmacol. 2012. PMID: 22930711

9

Pyrazole-based arylalkyne cathepsin S inhibitors. Part III: modification of P4 region.

Wiener JJ, Wickboldt AT, Nguyen S, Sun S, Rynberg R, Rizzolio M, Karlsson L, Edwards JP, Grice CA. Wiener JJ, et al. Among authors: sun s. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1070-4. doi: 10.1016/j.bmcl.2012.12.014. Epub 2012 Dec 21. Bioorg Med Chem Lett. 2013. PMID: 23313244

10

Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.

Soroosh P, Wu J, Xue X, Song J, Sutton SW, Sablad M, Yu J, Nelen MI, Liu X, Castro G, Luna R, Crawford S, Banie H, Dandridge RA, Deng X, Bittner A, Kuei C, Tootoonchi M, Rozenkrants N, Herman K, Gao J, Yang XV, Sachen K, Ngo K, Fung-Leung WP, Nguyen S, de Leon-Tabaldo A, Blevitt J, Zhang Y, Cummings MD, Rao T, Mani NS, Liu C, McKinnon M, Milla ME, Fourie AM, Sun S. Soroosh P, et al. Among authors: sun s. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12163-8. doi: 10.1073/pnas.1322807111. Epub 2014 Aug 4. Proc Natl Acad Sci U S A. 2014. PMID: 25092323 Free PMC article.

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