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Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury.
Cao W, Chen K, Bolkestein M, Yin Y, Verstegen MMA, Bijvelds MJC, Wang W, Tuysuz N, Ten Berge D, Sprengers D, Metselaar HJ, van der Laan LJW, Kwekkeboom J, Smits R, Peppelenbosch MP, Pan Q. Cao W, et al. Among authors: wang w. Gastroenterology. 2017 Oct;153(4):1133-1147. doi: 10.1053/j.gastro.2017.07.006. Epub 2017 Jul 14. Gastroenterology. 2017. PMID: 28716722
Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication.
Wang Y, Wang W, Xu L, Zhou X, Shokrollahi E, Felczak K, van der Laan LJ, Pankiewicz KW, Sprengers D, Raat NJ, Metselaar HJ, Peppelenbosch MP, Pan Q. Wang Y, et al. Among authors: wang w. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2834-48. doi: 10.1128/AAC.02700-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26926637 Free PMC article.
IFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN-stimulated genes.
Xu L, Zhou X, Wang W, Wang Y, Yin Y, Laan LJ, Sprengers D, Metselaar HJ, Peppelenbosch MP, Pan Q. Xu L, et al. Among authors: wang w, wang y. FASEB J. 2016 Oct;30(10):3352-3367. doi: 10.1096/fj.201600356R. Epub 2016 Jun 21. FASEB J. 2016. PMID: 27328944
We demonstrated that IRF1 effectively inhibits HEV replication through the activation of the JAK-STAT pathway, and the subsequent transcription of antiviral ISGs, but independent of IFN production.-Xu, L., Zhou, X., Wang, W., Wang, Y., Yin, Y., van der Laan, …
We demonstrated that IRF1 effectively inhibits HEV replication through the activation of the JAK-STAT pathway, and the subsequent transcript …
Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development.
Yin Y, Wang Y, Dang W, Xu L, Su J, Zhou X, Wang W, Felczak K, van der Laan LJ, Pankiewicz KW, van der Eijk AA, Bijvelds M, Sprengers D, de Jonge H, Koopmans MP, Metselaar HJ, Peppelenbosch MP, Pan Q. Yin Y, et al. Among authors: wang w, wang y. Antiviral Res. 2016 Sep;133:41-9. doi: 10.1016/j.antiviral.2016.07.017. Epub 2016 Jul 25. Antiviral Res. 2016. PMID: 27468950
The global burden of hepatitis E outbreaks: a systematic review.
Hakim MS, Wang W, Bramer WM, Geng J, Huang F, de Man RA, Peppelenbosch MP, Pan Q. Hakim MS, et al. Among authors: wang w. Liver Int. 2017 Jan;37(1):19-31. doi: 10.1111/liv.13237. Epub 2016 Sep 9. Liver Int. 2017. PMID: 27542764 Review.
Distinct Antiviral Potency of Sofosbuvir Against Hepatitis C and E Viruses.
Wang W, Hakim MS, Nair VP, de Ruiter PE, Huang F, Sprengers D, Van Der Laan LJ, Peppelenbosch MP, Surjit M, Pan Q. Wang W, et al. Gastroenterology. 2016 Dec;151(6):1251-1253. doi: 10.1053/j.gastro.2016.09.061. Epub 2016 Nov 1. Gastroenterology. 2016. PMID: 27815000 No abstract available.
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