Wickner W - Search Results

1

Sec17/Sec18 act twice, enhancing membrane fusion and then disassembling cis-SNARE complexes.

Song H, Orr A, Duan M, Merz AJ, Wickner W. Song H, et al. Among authors: wickner w. Elife. 2017 Jul 18;6:e26646. doi: 10.7554/eLife.26646. Elife. 2017. PMID: 28718762 Free PMC article.

2

Membranes linked by trans-SNARE complexes require lipids prone to non-bilayer structure for progression to fusion.

Zick M, Stroupe C, Orr A, Douville D, Wickner WT. Zick M, et al. Elife. 2014 Jan 1;3:e01879. doi: 10.7554/eLife.01879. Elife. 2014. PMID: 24596153 Free PMC article.

3

Sec17 can trigger fusion of trans-SNARE paired membranes without Sec18.

Zick M, Orr A, Schwartz ML, Merz AJ, Wickner WT. Zick M, et al. Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2290-7. doi: 10.1073/pnas.1506409112. Epub 2015 Apr 20. Proc Natl Acad Sci U S A. 2015. PMID: 25902545 Free PMC article.

4

A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion.

Thorngren N, Collins KM, Fratti RA, Wickner W, Merz AJ. Thorngren N, et al. Among authors: wickner w. EMBO J. 2004 Jul 21;23(14):2765-76. doi: 10.1038/sj.emboj.7600286. Epub 2004 Jul 8. EMBO J. 2004. PMID: 15241469 Free PMC article.

5

HOPS catalyzes the interdependent assembly of each vacuolar SNARE into a SNARE complex.

Orr A, Song H, Rusin SF, Kettenbach AN, Wickner W. Orr A, et al. Among authors: wickner w. Mol Biol Cell. 2017 Apr 1;28(7):975-983. doi: 10.1091/mbc.E16-10-0743. Epub 2017 Feb 1. Mol Biol Cell. 2017. PMID: 28148647 Free PMC article.

6

A short region upstream of the yeast vacuolar Qa-SNARE heptad-repeats promotes membrane fusion through enhanced SNARE complex assembly.

Song H, Wickner W. Song H, et al. Among authors: wickner w. Mol Biol Cell. 2017 Aug 15;28(17):2282-2289. doi: 10.1091/mbc.E17-04-0218. Epub 2017 Jun 21. Mol Biol Cell. 2017. PMID: 28637767 Free PMC article.

7

HOPS recognizes each SNARE, assembling ternary trans-complexes for rapid fusion upon engagement with the 4th SNARE.

Song H, Orr AS, Lee M, Harner ME, Wickner WT. Song H, et al. Elife. 2020 Jan 21;9:e53559. doi: 10.7554/eLife.53559. Elife. 2020. PMID: 31961324 Free PMC article.

8

Sec17/Sec18 can support membrane fusion without help from completion of SNARE zippering.

Song H, Torng TL, Orr AS, Brunger AT, Wickner WT. Song H, et al. Elife. 2021 May 4;10:e67578. doi: 10.7554/eLife.67578. Elife. 2021. PMID: 33944780 Free PMC article.

9

Fusion of tethered membranes can be driven by Sec18/NSF and Sec17/αSNAP without HOPS.

Song H, Wickner WT. Song H, et al. Among authors: wickner wt. Elife. 2021 Oct 26;10:e73240. doi: 10.7554/eLife.73240. Elife. 2021. PMID: 34698639 Free PMC article.

10

Tethering guides fusion-competent trans-SNARE assembly.

Song H, Wickner W. Song H, et al. Among authors: wickner w. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13952-13957. doi: 10.1073/pnas.1907640116. Epub 2019 Jun 24. Proc Natl Acad Sci U S A. 2019. PMID: 31235584 Free PMC article.

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