David SS - Search Results

1

Structure-Activity Relationships Reveal Key Features of 8-Oxoguanine: A Mismatch Detection by the MutY Glycosylase.

Manlove AH, McKibbin PL, Doyle EL, Majumdar C, Hamm ML, David SS. Manlove AH, et al. Among authors: david ss. ACS Chem Biol. 2017 Sep 15;12(9):2335-2344. doi: 10.1021/acschembio.7b00389. Epub 2017 Aug 8. ACS Chem Biol. 2017. PMID: 28723094 Free PMC article.

2

Single-turnover and pre-steady-state kinetics of the reaction of the adenine glycosylase MutY with mismatch-containing DNA substrates.

Porello SL, Leyes AE, David SS. Porello SL, et al. Among authors: david ss. Biochemistry. 1998 Oct 20;37(42):14756-64. doi: 10.1021/bi981594+. Biochemistry. 1998. PMID: 9778350

3

Base-excision repair of oxidative DNA damage.

David SS, O'Shea VL, Kundu S. David SS, et al. Nature. 2007 Jun 21;447(7147):941-50. doi: 10.1038/nature05978. Nature. 2007. PMID: 17581577 Free PMC article. Review.

4

Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY.

Livingston AL, O'Shea VL, Kim T, Kool ET, David SS. Livingston AL, et al. Among authors: david ss. Nat Chem Biol. 2008 Jan;4(1):51-8. doi: 10.1038/nchembio.2007.40. Epub 2007 Nov 18. Nat Chem Biol. 2008. PMID: 18026095 Free PMC article.

5

Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer.

Kundu S, Brinkmeyer MK, Livingston AL, David SS. Kundu S, et al. Among authors: david ss. DNA Repair (Amst). 2009 Dec 3;8(12):1400-10. doi: 10.1016/j.dnarep.2009.09.009. DNA Repair (Amst). 2009. PMID: 19836313 Free PMC article.

6

Ser 524 is a phosphorylation site in MUTYH and Ser 524 mutations alter 8-oxoguanine (OG): a mismatch recognition.

Kundu S, Brinkmeyer MK, Eigenheer RA, David SS. Kundu S, et al. Among authors: david ss. DNA Repair (Amst). 2010 Oct 5;9(10):1026-37. doi: 10.1016/j.dnarep.2010.07.002. Epub 2010 Aug 17. DNA Repair (Amst). 2010. PMID: 20724227 Free PMC article.

7

Profiling base excision repair glycosylases with synthesized transition state analogs.

Chu AM, Fettinger JC, David SS. Chu AM, et al. Among authors: david ss. Bioorg Med Chem Lett. 2011 Sep 1;21(17):4969-72. doi: 10.1016/j.bmcl.2011.05.085. Epub 2011 May 30. Bioorg Med Chem Lett. 2011. PMID: 21689934 Free PMC article.

8

Surprising repair activities of nonpolar analogs of 8-oxoG expose features of recognition and catalysis by base excision repair glycosylases.

McKibbin PL, Kobori A, Taniguchi Y, Kool ET, David SS. McKibbin PL, et al. Among authors: david ss. J Am Chem Soc. 2012 Jan 25;134(3):1653-61. doi: 10.1021/ja208510m. Epub 2012 Jan 9. J Am Chem Soc. 2012. PMID: 22175854 Free PMC article.

9

Catalytic contributions of key residues in the adenine glycosylase MutY revealed by pH-dependent kinetics and cellular repair assays.

Brinkmeyer MK, Pope MA, David SS. Brinkmeyer MK, et al. Among authors: david ss. Chem Biol. 2012 Feb 24;19(2):276-86. doi: 10.1016/j.chembiol.2011.11.011. Chem Biol. 2012. PMID: 22365610 Free PMC article.

10

NEIL1 binding to DNA containing 2'-fluorothymidine glycol stereoisomers and the effect of editing.

Onizuka K, Yeo J, David SS, Beal PA. Onizuka K, et al. Among authors: david ss. Chembiochem. 2012 Jun 18;13(9):1338-48. doi: 10.1002/cbic.201200139. Epub 2012 May 25. Chembiochem. 2012. PMID: 22639086 Free PMC article.

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