Hernandez-Borrero LJ - Search Results

1

CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA.

Hernandez-Borrero LJ, Zhang S, Lulla A, Dicker DT, El-Deiry WS. Hernandez-Borrero LJ, et al. Cell Cycle. 2018;17(5):557-567. doi: 10.1080/15384101.2017.1346762. Epub 2018 Feb 19. Cell Cycle. 2018. PMID: 28749203 Free PMC article.

2

A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53.

Hernandez Borrero L, Dicker DT, Santiago J, Sanders J, Tian X, Ahsan N, Lev A, Zhou L, El-Deiry WS. Hernandez Borrero L, et al. Elife. 2021 Jul 29;10:e70429. doi: 10.7554/eLife.70429. Elife. 2021. PMID: 34324416 Free PMC article.

3

Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer.

Zhang S, Carlsen L, Hernandez Borrero L, Seyhan AA, Tian X, El-Deiry WS. Zhang S, et al. Biomolecules. 2022 Apr 6;12(4):548. doi: 10.3390/biom12040548. Biomolecules. 2022. PMID: 35454137 Free PMC article. Review.

4

Small-molecule CB002 restores p53 pathway signaling and represses colorectal cancer cell growth.

Richardson C, Zhang S, Hernandez Borrero LJ, El-Deiry WS. Richardson C, et al. Among authors: hernandez borrero lj. Cell Cycle. 2017 Sep 17;16(18):1719-1725. doi: 10.1080/15384101.2017.1356514. Epub 2017 Jul 27. Cell Cycle. 2017. PMID: 28749206 Free PMC article.

5

Bcl-2 Protein Targeting by the p53/p21 Complex-Letter.

Hernandez Borrero LJ, Sikder R, Lulla A, Gokare P, Del Valle PR, Tian X, Zhang S, Abbosh PH, El-Deiry WS. Hernandez Borrero LJ, et al. Cancer Res. 2018 May 15;78(10):2770-2771. doi: 10.1158/0008-5472.CAN-17-2556. Epub 2018 Apr 27. Cancer Res. 2018. PMID: 29703721 No abstract available.

6

Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting.

Hernández Borrero LJ, El-Deiry WS. Hernández Borrero LJ, et al. Biochim Biophys Acta Rev Cancer. 2021 Aug;1876(1):188556. doi: 10.1016/j.bbcan.2021.188556. Epub 2021 Apr 29. Biochim Biophys Acta Rev Cancer. 2021. PMID: 33932560 Free PMC article. Review.

7

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells.

Carlsen L, Schorl C, Huntington K, Hernandez-Borrero L, Jhaveri A, Zhang S, Zhou L, El-Deiry WS. Carlsen L, et al. Oncotarget. 2021 Sep 28;12(20):2006-2021. doi: 10.18632/oncotarget.28075. eCollection 2021 Sep 28. Oncotarget. 2021. PMID: 34611476 Free PMC article.

8

Targeting the Integrated Stress Response in Cancer Therapy.

Tian X, Zhang S, Zhou L, Seyhan AA, Hernandez Borrero L, Zhang Y, El-Deiry WS. Tian X, et al. Front Pharmacol. 2021 Sep 24;12:747837. doi: 10.3389/fphar.2021.747837. eCollection 2021. Front Pharmacol. 2021. PMID: 34630117 Free PMC article. Review.

9

Therapeutic Targeting of Autophagy in Pancreatic Ductal Adenocarcinoma.

Raufi AG, Liguori NR, Carlsen L, Parker C, Hernandez Borrero L, Zhang S, Tian X, Louie A, Zhou L, Seyhan AA, El-Deiry WS. Raufi AG, et al. Front Pharmacol. 2021 Nov 30;12:751568. doi: 10.3389/fphar.2021.751568. eCollection 2021. Front Pharmacol. 2021. PMID: 34916936 Free PMC article. Review.

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