Hediger MA - Search Results

1

A novel proton transfer mechanism in the SLC11 family of divalent metal ion transporters.

Pujol-Giménez J, Hediger MA, Gyimesi G. Pujol-Giménez J, et al. Among authors: hediger ma. Sci Rep. 2017 Jul 28;7(1):6194. doi: 10.1038/s41598-017-06446-y. Sci Rep. 2017. PMID: 28754960 Free PMC article.

2

Mammalian iron transporters: families SLC11 and SLC40.

Montalbetti N, Simonin A, Kovacs G, Hediger MA. Montalbetti N, et al. Among authors: hediger ma. Mol Aspects Med. 2013 Apr-Jun;34(2-3):270-87. doi: 10.1016/j.mam.2013.01.002. Mol Aspects Med. 2013. PMID: 23506870 Review.

3

Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2.

Montalbetti N, Simonin A, Simonin C, Awale M, Reymond JL, Hediger MA. Montalbetti N, et al. Among authors: hediger ma. Biochem Pharmacol. 2015 Aug 1;96(3):216-24. doi: 10.1016/j.bcp.2015.05.002. Epub 2015 Jun 3. Biochem Pharmacol. 2015. PMID: 26047847

4

A Call for Systematic Research on Solute Carriers.

César-Razquin A, Snijder B, Frappier-Brinton T, Isserlin R, Gyimesi G, Bai X, Reithmeier RA, Hepworth D, Hediger MA, Edwards AM, Superti-Furga G. César-Razquin A, et al. Among authors: hediger ma. Cell. 2015 Jul 30;162(3):478-87. doi: 10.1016/j.cell.2015.07.022. Cell. 2015. PMID: 26232220 Free article. Review.

5

Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method.

Simonin C, Awale M, Brand M, van Deursen R, Schwartz J, Fine M, Kovacs G, Häfliger P, Gyimesi G, Sithampari A, Charles RP, Hediger MA, Reymond JL. Simonin C, et al. Among authors: hediger ma. Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14748-52. doi: 10.1002/anie.201507320. Epub 2015 Oct 12. Angew Chem Int Ed Engl. 2015. PMID: 26457814

6

The Hydroxyl Side Chain of a Highly Conserved Serine Residue Is Required for Cation Selectivity and Substrate Transport in the Glial Glutamate Transporter GLT-1/SLC1A2.

Simonin A, Montalbetti N, Gyimesi G, Pujol-Giménez J, Hediger MA. Simonin A, et al. Among authors: hediger ma. J Biol Chem. 2015 Dec 18;290(51):30464-74. doi: 10.1074/jbc.M115.689836. Epub 2015 Oct 19. J Biol Chem. 2015. PMID: 26483543 Free PMC article.

7

Reassessment of the Transport Mechanism of the Human Zinc Transporter SLC39A2.

Franz MC, Pujol-Giménez J, Montalbetti N, Fernandez-Tenorio M, DeGrado TR, Niggli E, Romero MF, Hediger MA. Franz MC, et al. Among authors: hediger ma. Biochemistry. 2018 Jul 3;57(26):3976-3986. doi: 10.1021/acs.biochem.8b00511. Epub 2018 Jun 7. Biochemistry. 2018. PMID: 29791142 Free PMC article.

8

Amino acid transporters revisited: New views in health and disease.

Kandasamy P, Gyimesi G, Kanai Y, Hediger MA. Kandasamy P, et al. Among authors: hediger ma. Trends Biochem Sci. 2018 Oct;43(10):752-789. doi: 10.1016/j.tibs.2018.05.003. Epub 2018 Aug 31. Trends Biochem Sci. 2018. PMID: 30177408 Review.

9

ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain.

Bulla M, Gyimesi G, Kim JH, Bhardwaj R, Hediger MA, Frieden M, Demaurex N. Bulla M, et al. Among authors: hediger ma. J Physiol. 2019 Jan;597(2):561-582. doi: 10.1113/JP277079. Epub 2018 Nov 28. J Physiol. 2019. PMID: 30382595 Free PMC article.

10

Unraveling the structural elements of pH sensitivity and substrate binding in the human zinc transporter SLC39A2 (ZIP2).

Gyimesi G, Albano G, Fuster DG, Hediger MA, Pujol-Giménez J. Gyimesi G, et al. Among authors: hediger ma. J Biol Chem. 2019 May 17;294(20):8046-8063. doi: 10.1074/jbc.RA118.006113. Epub 2019 Mar 26. J Biol Chem. 2019. PMID: 30914478 Free PMC article.

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