Kruse LI - Search Results

1

6,7-Dichloro-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline . A structurally novel beta-adrenergic receptor blocking agent.

Kaiser C, Oh HJ, Garcia-Slanga BJ, Sulpizio AC, Hieble JP, Wawro JE, Kruse LI. Kaiser C, et al. Among authors: kruse li. J Med Chem. 1986 Nov;29(11):2381-4. doi: 10.1021/jm00161a039. J Med Chem. 1986. PMID: 2878080

2

Multisubstrate inhibitors of dopamine beta-hydroxylase. 2. Structure-activity relationships at the phenethylamine binding site.

Kruse LI, Kaiser C, DeWolf WE Jr, Frazee JS, Ross ST, Wawro J, Wise M, Flaim KE, Sawyer JL, Erickson RW, et al. Kruse LI, et al. J Med Chem. 1987 Mar;30(3):486-94. doi: 10.1021/jm00386a008. J Med Chem. 1987. PMID: 3820219

3

Beta-substituted phenethylamines as high-affinity mechanism-based inhibitors of dopamine beta-hydroxylase.

Kruse LI, Kaiser C, DeWolf WE Jr, Chambers PA, Goodhart PJ, Ezekiel M, Ohlstein EH. Kruse LI, et al. J Med Chem. 1988 Apr;31(4):704-6. doi: 10.1021/jm00399a002. J Med Chem. 1988. PMID: 3351845 No abstract available.

4

Substituted 1-benzylimidazole-2-thiols as potent and orally active inhibitors of dopamine beta-hydroxylase.

Kruse LI, Kaiser C, DeWolf WE Jr, Frazee JS, Erickson RW, Ezekiel M, Ohlstein EH, Ruffolo RR Jr, Berkowitz BA. Kruse LI, et al. J Med Chem. 1986 Jun;29(6):887-9. doi: 10.1021/jm00156a002. J Med Chem. 1986. PMID: 3712378 No abstract available.

5

Multisubstrate inhibitors of dopamine beta-hydroxylase. 1. Some 1-phenyl and 1-phenyl-bridged derivatives of imidazole-2-thione.

Kruse LI, Kaiser C, DeWolf WE Jr, Frazee JS, Garvey E, Hilbert EL, Faulkner WA, Flaim KE, Sawyer JL, Berkowitz BA. Kruse LI, et al. J Med Chem. 1986 Dec;29(12):2465-72. doi: 10.1021/jm00162a008. J Med Chem. 1986. PMID: 3783606

6

Some benzyl-substituted imidazoles, triazoles, tetrazoles, pyridinethiones, and structural relatives as multisubstrate inhibitors of dopamine beta-hydroxylase. 4. Structure-activity relationships at the copper binding site.

Kruse LI, Kaiser C, DeWolf WE, Finkelstein JA, Frazee JS, Hilbert EL, Ross ST, Flaim KE, Sawyer JL. Kruse LI, et al. J Med Chem. 1990 Feb;33(2):781-9. doi: 10.1021/jm00164a051. J Med Chem. 1990. PMID: 2299645

7

Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogues.

Kruse LI, Ladd DL, Harrsch PB, McCabe FL, Mong SM, Faucette L, Johnson R. Kruse LI, et al. J Med Chem. 1989 Feb;32(2):409-17. doi: 10.1021/jm00122a020. J Med Chem. 1989. PMID: 2913301

8

Inhibitors of dopamine beta-hydroxylase. 3. Some 1-(pyridylmethyl)imidazole-2-thiones.

Ross ST, Kruse LI, Ohlstein EH, Erickson RW, Ezekiel M, Flaim KE, Sawyer JL, Berkowitz BA. Ross ST, et al. Among authors: kruse li. J Med Chem. 1987 Aug;30(8):1309-13. doi: 10.1021/jm00391a008. J Med Chem. 1987. PMID: 3612682

9

ATP-citrate lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-beta-lactam containing analogues of citric acid as potential tight-binding inhibitors.

Dolle RE, McNair D, Hughes MJ, Kruse LI, Eggelston D, Saxty BA, Wells TN, Groot PH. Dolle RE, et al. Among authors: kruse li. J Med Chem. 1992 Dec 25;35(26):4875-84. doi: 10.1021/jm00104a014. J Med Chem. 1992. PMID: 1479587

10

Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase.

Ator MA, Schmidt SJ, Adams JL, Dolle RE, Kruse LI, Frey CL, Barone JM. Ator MA, et al. Among authors: kruse li. J Med Chem. 1992 Jan;35(1):100-6. doi: 10.1021/jm00079a012. J Med Chem. 1992. PMID: 1732516

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