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Page 1
aPKC Cycles between Functionally Distinct PAR Protein Assemblies to Drive Cell Polarity.
Rodriguez J, Peglion F, Martin J, Hubatsch L, Reich J, Hirani N, Gubieda AG, Roffey J, Fernandes AR, St Johnston D, Ahringer J, Goehring NW. Rodriguez J, et al. Among authors: roffey j. Dev Cell. 2017 Aug 21;42(4):400-415.e9. doi: 10.1016/j.devcel.2017.07.007. Epub 2017 Aug 3. Dev Cell. 2017. PMID: 28781174 Free PMC article.
Protein kinase C intervention: the state of play.
Roffey J, Rosse C, Linch M, Hibbert A, McDonald NQ, Parker PJ. Roffey J, et al. Curr Opin Cell Biol. 2009 Apr;21(2):268-79. doi: 10.1016/j.ceb.2009.01.019. Epub 2009 Feb 23. Curr Opin Cell Biol. 2009. PMID: 19233632 Review.
Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes.
Kjær S, Linch M, Purkiss A, Kostelecky B, Knowles PP, Rosse C, Riou P, Soudy C, Kaye S, Patel B, Soriano E, Murray-Rust J, Barton C, Dillon C, Roffey J, Parker PJ, McDonald NQ. Kjær S, et al. Among authors: roffey j. Biochem J. 2013 Apr 15;451(2):329-42. doi: 10.1042/BJ20121871. Biochem J. 2013. PMID: 23418854
Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment.
Mirza AN, Fry MA, Urman NM, Atwood SX, Roffey J, Ott GR, Chen B, Lee A, Brown AS, Aasi SZ, Hollmig T, Ator MA, Dorsey BD, Ruggeri BR, Zificsak CA, Sirota M, Tang JY, Butte A, Epstein E, Sarin KY, Oro AE. Mirza AN, et al. Among authors: roffey j. JCI Insight. 2017 Nov 2;2(21):e97071. doi: 10.1172/jci.insight.97071. JCI Insight. 2017. PMID: 29093271 Free PMC article.
Dynamic telomerase gene suppression via network effects of GSK3 inhibition.
Bilsland AE, Hoare S, Stevenson K, Plumb J, Gomez-Roman N, Cairney C, Burns S, Lafferty-Whyte K, Roffey J, Hammonds T, Keith WN. Bilsland AE, et al. Among authors: roffey j. PLoS One. 2009 Jul 31;4(7):e6459. doi: 10.1371/journal.pone.0006459. PLoS One. 2009. PMID: 19649288 Free PMC article.
Cancer cell senescence: a new frontier in drug development.
Cairney CJ, Bilsland AE, Evans TR, Roffey J, Bennett DC, Narita M, Torrance CJ, Keith WN. Cairney CJ, et al. Among authors: roffey j. Drug Discov Today. 2012 Mar;17(5-6):269-76. doi: 10.1016/j.drudis.2012.01.019. Epub 2012 Jan 31. Drug Discov Today. 2012. PMID: 22314100 Review.
18 results