Piomelli D - Search Results

1

Complete Acid Ceramidase ablation prevents cancer-initiating cell formation in melanoma cells.

Lai M, Realini N, La Ferla M, Passalacqua I, Matteoli G, Ganesan A, Pistello M, Mazzanti CM, Piomelli D. Lai M, et al. Among authors: piomelli d. Sci Rep. 2017 Aug 7;7(1):7411. doi: 10.1038/s41598-017-07606-w. Sci Rep. 2017. PMID: 28785021 Free PMC article.

2

Proinflammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages.

Zhu C, Solorzano C, Sahar S, Realini N, Fung E, Sassone-Corsi P, Piomelli D. Zhu C, et al. Among authors: piomelli d. Mol Pharmacol. 2011 Apr;79(4):786-92. doi: 10.1124/mol.110.070201. Epub 2011 Jan 13. Mol Pharmacol. 2011. PMID: 21233218 Free PMC article.

3

Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models.

Sasso O, Moreno-Sanz G, Martucci C, Realini N, Dionisi M, Mengatto L, Duranti A, Tarozzo G, Tarzia G, Mor M, Bertorelli R, Reggiani A, Piomelli D. Sasso O, et al. Among authors: piomelli d. Pain. 2013 Mar;154(3):350-360. doi: 10.1016/j.pain.2012.10.018. Epub 2012 Nov 2. Pain. 2013. PMID: 23218523 Free PMC article.

4

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity.

Realini N, Solorzano C, Pagliuca C, Pizzirani D, Armirotti A, Luciani R, Costi MP, Bandiera T, Piomelli D. Realini N, et al. Among authors: piomelli d. Sci Rep. 2013;3:1035. doi: 10.1038/srep01035. Epub 2013 Jan 8. Sci Rep. 2013. PMID: 23301156 Free PMC article.

5

Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR).

Pizzirani D, Pagliuca C, Realini N, Branduardi D, Bottegoni G, Mor M, Bertozzi F, Scarpelli R, Piomelli D, Bandiera T. Pizzirani D, et al. Among authors: piomelli d. J Med Chem. 2013 May 9;56(9):3518-30. doi: 10.1021/jm301879g. Epub 2013 Apr 24. J Med Chem. 2013. PMID: 23614460 Free article.

6

Sample preparation and orthogonal chromatography for broad polarity range plasma metabolomics: application to human subjects with neurodegenerative dementia.

Armirotti A, Basit A, Realini N, Caltagirone C, Bossù P, Spalletta G, Piomelli D. Armirotti A, et al. Among authors: piomelli d. Anal Biochem. 2014 Jun 15;455:48-54. doi: 10.1016/j.ab.2014.03.019. Epub 2014 Apr 4. Anal Biochem. 2014. PMID: 24708938 Free article.

7

Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase.

Pizzirani D, Bach A, Realini N, Armirotti A, Mengatto L, Bauer I, Girotto S, Pagliuca C, De Vivo M, Summa M, Ribeiro A, Piomelli D. Pizzirani D, et al. Among authors: piomelli d. Angew Chem Int Ed Engl. 2015 Jan 7;54(2):485-9. doi: 10.1002/anie.201409042. Epub 2014 Nov 13. Angew Chem Int Ed Engl. 2015. PMID: 25395373 Free PMC article.

8

Methamphetamine accelerates cellular senescence through stimulation of de novo ceramide biosynthesis.

Astarita G, Avanesian A, Grimaldi B, Realini N, Justinova Z, Panlilio LV, Basit A, Goldberg SR, Piomelli D. Astarita G, et al. Among authors: piomelli d. PLoS One. 2015 Feb 11;10(2):e0116961. doi: 10.1371/journal.pone.0116961. eCollection 2015. PLoS One. 2015. PMID: 25671639 Free PMC article.

9

Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION.

Realini N, Palese F, Pizzirani D, Pontis S, Basit A, Bach A, Ganesan A, Piomelli D. Realini N, et al. Among authors: piomelli d. J Biol Chem. 2016 Jan 29;291(5):2422-34. doi: 10.1074/jbc.M115.666909. Epub 2015 Nov 9. J Biol Chem. 2016. PMID: 26553872 Free PMC article.

10

Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies.

Bach A, Pizzirani D, Realini N, Vozella V, Russo D, Penna I, Melzig L, Scarpelli R, Piomelli D. Bach A, et al. Among authors: piomelli d. J Med Chem. 2015 Dec 10;58(23):9258-72. doi: 10.1021/acs.jmedchem.5b01188. Epub 2015 Nov 23. J Med Chem. 2015. PMID: 26560855 Free article.

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