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Methods to evaluate and improve the injection site tolerability of intravenous formulations prior to first-in-human testing.
Eichenbaum G, Zhou J, De Smedt A, De Jonghe S, Looszova A, Arien T, Van Goethem F, Vervoort I, Shukla U, Lammens L. Eichenbaum G, et al. Among authors: de jonghe s, de smedt a. J Pharmacol Toxicol Methods. 2013 Nov-Dec;68(3):394-406. doi: 10.1016/j.vascn.2013.08.002. Epub 2013 Aug 8. J Pharmacol Toxicol Methods. 2013. PMID: 23933112
Modeling the Time Course of the Tissue Responses to Intramuscular Long-acting Paliperidone Palmitate Nano-/Microcrystals and Polystyrene Microspheres in the Rat.
Darville N, van Heerden M, Erkens T, De Jonghe S, Vynckier A, De Meulder M, Vermeulen A, Sterkens P, Annaert P, Van den Mooter G. Darville N, et al. Among authors: de jonghe s, de meulder m. Toxicol Pathol. 2016 Feb;44(2):189-210. doi: 10.1177/0192623315618291. Epub 2015 Dec 23. Toxicol Pathol. 2016. PMID: 26698322
159 results