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A phase 2 study of Chronocort, a modified-release formulation of hydrocortisone, in the treatment of adults with classic congenital adrenal hyperplasia.
Mallappa A, Sinaii N, Kumar P, Whitaker MJ, Daley LA, Digweed D, Eckland DJ, Van Ryzin C, Nieman LK, Arlt W, Ross RJ, Merke DP. Mallappa A, et al. Among authors: digweed d. J Clin Endocrinol Metab. 2015 Mar;100(3):1137-45. doi: 10.1210/jc.2014-3809. Epub 2014 Dec 11. J Clin Endocrinol Metab. 2015. PMID: 25494662 Free PMC article. Clinical Trial.
Development and testing in healthy adults of oral hydrocortisone granules with taste masking for the treatment of neonates and infants with adrenal insufficiency.
Whitaker MJ, Spielmann S, Digweed D, Huatan H, Eckland D, Johnson TN, Tucker G, Krude H, Blankenstein O, Ross RJ. Whitaker MJ, et al. Among authors: digweed d. J Clin Endocrinol Metab. 2015 Apr;100(4):1681-8. doi: 10.1210/jc.2014-4060. Epub 2015 Feb 3. J Clin Endocrinol Metab. 2015. PMID: 25646792 Clinical Trial.
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo.
Nikolaou N, Arvaniti A, Appanna N, Sharp A, Hughes BA, Digweed D, Whitaker MJ, Ross R, Arlt W, Penning TM, Morris K, George S, Keevil BG, Hodson L, Gathercole LL, Tomlinson JW. Nikolaou N, et al. Among authors: digweed d. J Endocrinol. 2020 May;245(2):207-218. doi: 10.1530/JOE-19-0473. J Endocrinol. 2020. PMID: 32106090 Free PMC article.