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Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation.
di Salvo ML, Mastrangelo M, Nogués I, Tolve M, Paiardini A, Carducci C, Mei D, Montomoli M, Tramonti A, Guerrini R, Contestabile R, Leuzzi V. di Salvo ML, et al. Among authors: paiardini a. Mol Genet Metab. 2017 Sep;122(1-2):135-142. doi: 10.1016/j.ymgme.2017.08.003. Epub 2017 Aug 12. Mol Genet Metab. 2017. PMID: 28818555
AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.
Asteriti IA, Polverino F, Stagni V, Sterbini V, Ascanelli C, Naso FD, Mastrangelo A, Rosa A, Paiardini A, Lindon C, Guarguaglini G. Asteriti IA, et al. Among authors: paiardini a. Life Sci Alliance. 2023 Feb 16;6(5):e202201726. doi: 10.26508/lsa.202201726. Print 2023 May. Life Sci Alliance. 2023. PMID: 36797043 Free PMC article.
A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression.
Di Nisio E, Licursi V, Mannironi C, Buglioni V, Paiardini A, Robusti G, Noberini R, Bonaldi T, Negri R. Di Nisio E, et al. Among authors: paiardini a. Cancer Gene Ther. 2023 Jun;30(6):822-832. doi: 10.1038/s41417-022-00584-w. Epub 2023 Jan 26. Cancer Gene Ther. 2023. PMID: 36697763 Free PMC article.
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8.
Fiorentino F, Sementilli S, Menna M, Turrisi F, Tomassi S, Pellegrini FR, Iuzzolino A, D'Acunzo F, Feoli A, Wapenaar H, Taraglio S, Fraschetti C, Del Bufalo D, Sbardella G, Dekker FJ, Paiardini A, Trisciuoglio D, Mai A, Rotili D. Fiorentino F, et al. Among authors: paiardini a. J Med Chem. 2023 May 25;66(10):6591-6616. doi: 10.1021/acs.jmedchem.2c01937. Epub 2023 May 8. J Med Chem. 2023. PMID: 37155735 Free PMC article.
Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1.
Abdelbaki A, Ascanelli C, Okoye CN, Akman HB, Janson G, Min M, Marcozzi C, Hagting A, Grant R, De Luca M, Asteriti IA, Guarguaglini G, Paiardini A, Lindon C. Abdelbaki A, et al. Among authors: paiardini a. Life Sci Alliance. 2022 Nov 30;6(2):e202201372. doi: 10.26508/lsa.202201372. Print 2023 Feb. Life Sci Alliance. 2022. PMID: 36450448 Free PMC article.
134 results