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Page 1
Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT.
Aguilar JI, Dunn M, Mingote S, Karam CS, Farino ZJ, Sonders MS, Choi SJ, Grygoruk A, Zhang Y, Cela C, Choi BJ, Flores J, Freyberg RJ, McCabe BD, Mosharov EV, Krantz DE, Javitch JA, Sulzer D, Sames D, Rayport S, Freyberg Z. Aguilar JI, et al. Neuron. 2017 Aug 30;95(5):1074-1088.e7. doi: 10.1016/j.neuron.2017.07.038. Epub 2017 Aug 17. Neuron. 2017. PMID: 28823729 Free PMC article.
Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain.
Freyberg Z, Sonders MS, Aguilar JI, Hiranita T, Karam CS, Flores J, Pizzo AB, Zhang Y, Farino ZJ, Chen A, Martin CA, Kopajtic TA, Fei H, Hu G, Lin YY, Mosharov EV, McCabe BD, Freyberg R, Wimalasena K, Hsin LW, Sames D, Krantz DE, Katz JL, Sulzer D, Javitch JA. Freyberg Z, et al. Among authors: aguilar ji. Nat Commun. 2016 Feb 16;7:10652. doi: 10.1038/ncomms10652. Nat Commun. 2016. PMID: 26879809 Free PMC article.
Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells.
Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z. Carter SD, et al. Among authors: aguilar ji. Sci Adv. 2020 Apr 1;6(14):eaay9572. doi: 10.1126/sciadv.aay9572. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32270040 Free PMC article.
A network of phosphatidylinositol (4,5)-bisphosphate (PIP2) binding sites on the dopamine transporter regulates amphetamine behavior in Drosophila Melanogaster.
Belovich AN, Aguilar JI, Mabry SJ, Cheng MH, Zanella D, Hamilton PJ, Stanislowski DJ, Shekar A, Foster JD, Bahar I, Matthies HJG, Galli A. Belovich AN, et al. Among authors: aguilar ji. Mol Psychiatry. 2021 Aug;26(8):4417-4430. doi: 10.1038/s41380-019-0620-0. Epub 2019 Dec 3. Mol Psychiatry. 2021. PMID: 31796894 Free PMC article.
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease.
Herborg F, Jensen KL, Tolstoy S, Arends NV, Posselt LP, Shekar A, Aguilar JI, Lund VK, Erreger K, Rickhag M, Lycas MD, Lonsdale MN, Rahbek-Clemmensen T, Sørensen AT, Newman AH, Løkkegaard A, Kjærulff O, Werge T; iPSYCH researchers; Møller LB, Matthies HJ, Galli A, Hjermind LE, Gether U. Herborg F, et al. Among authors: aguilar ji. JCI Insight. 2021 Sep 22;6(18):e151496. doi: 10.1172/jci.insight.151496. JCI Insight. 2021. PMID: 34375312 Free PMC article.
Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3.
Campbell NG, Shekar A, Aguilar JI, Peng D, Navratna V, Yang D, Morley AN, Duran AM, Galli G, O'Grady B, Ramachandran R, Sutcliffe JS, Sitte HH, Erreger K, Meiler J, Stockner T, Bellan LM, Matthies HJG, Gouaux E, Mchaourab HS, Galli A. Campbell NG, et al. Among authors: aguilar ji. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3853-3862. doi: 10.1073/pnas.1816247116. Epub 2019 Feb 12. Proc Natl Acad Sci U S A. 2019. PMID: 30755521 Free PMC article.
Syntaxin 1 Ser14 phosphorylation is required for nonvesicular dopamine release.
Shekar A, Mabry SJ, Cheng MH, Aguilar JI, Patel S, Zanella D, Saleeby DP, Zhu Y, Romanazzi T, Ulery-Reynolds P, Bahar I, Carter AM, Matthies HJG, Galli A. Shekar A, et al. Among authors: aguilar ji. Sci Adv. 2023 Jan 13;9(2):eadd8417. doi: 10.1126/sciadv.add8417. Epub 2023 Jan 11. Sci Adv. 2023. PMID: 36630507 Free PMC article.