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Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.
Dai CL, Tiwari AK, Wu CP, Su XD, Wang SR, Liu DG, Ashby CR Jr, Huang Y, Robey RW, Liang YJ, Chen LM, Shi CJ, Ambudkar SV, Chen ZS, Fu LW. Dai CL, et al. Among authors: tiwari ak. Cancer Res. 2008 Oct 1;68(19):7905-14. doi: 10.1158/0008-5472.CAN-08-0499. Cancer Res. 2008. PMID: 18829547 Free PMC article.
2,3-Diaryl-3H-imidazo[4,5-b]pyridine derivatives as potential anticancer and anti-inflammatory agents.
Marie Kirwen E, Batra T, Karthikeyan C, Deora GS, Rathore V, Mulakayala C, Mulakayala N, Nusbaum AC, Chen J, Amawi H, McIntosh K, Sahabjada, Shivnath N, Chowarsia D, Sharma N, Arshad M, Trivedi P, Tiwari AK. Marie Kirwen E, et al. Among authors: tiwari ak. Acta Pharm Sin B. 2017 Jan;7(1):73-79. doi: 10.1016/j.apsb.2016.05.003. Epub 2016 Aug 6. Acta Pharm Sin B. 2017. PMID: 28119811 Free PMC article.
982 results