Barndt R - Search Results

1

Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity.

Tseng CC, Jia B, Barndt R, Gu Y, Chen CY, Tseng IC, Su SF, Wang JK, Johnson MD, Lin CY. Tseng CC, et al. Among authors: barndt r. PLoS One. 2017 Aug 22;12(8):e0183507. doi: 10.1371/journal.pone.0183507. eCollection 2017. PLoS One. 2017. PMID: 28829816 Free PMC article.

2

Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner.

Su HC, Liang YA, Lai YJ, Chiu YL, Barndt RB, Shiao F, Chang HD, Lu DD, Huang N, Tseng CC, Wang JK, Lee MS, Johnson MD, Huang SM, Lin CY. Su HC, et al. PLoS One. 2016 Dec 9;11(12):e0167894. doi: 10.1371/journal.pone.0167894. eCollection 2016. PLoS One. 2016. PMID: 27936035 Free PMC article.

3

Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2.

Chiu YL, Wu YY, Barndt RB, Yeo YH, Lin YW, Sytwo HP, Liu HC, Xu Y, Jia B, Wang JK, Johnson MD, Lin CY. Chiu YL, et al. J Enzyme Inhib Med Chem. 2019 Dec;34(1):692-702. doi: 10.1080/14756366.2019.1577831. J Enzyme Inhib Med Chem. 2019. PMID: 30777474 Free PMC article.

4

The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane.

Tseng CC, Jia B, Barndt RB, Dai YH, Chen YH, Du PA, Wang JK, Tang HJ, Lin CY, Johnson MD. Tseng CC, et al. PLoS One. 2020 Feb 12;15(2):e0228874. doi: 10.1371/journal.pone.0228874. eCollection 2020. PLoS One. 2020. PMID: 32049977 Free PMC article.

5

Mild acidity likely accelerates the physiological matriptase autoactivation process: a comparative study between spontaneous and acid-induced matriptase zymogen activation.

Jia B, Thompson HA, Barndt RB, Chiu YL, Lee MJ, Lee SC, Wang JK, Tang HJ, Lin CY, Johnson MD. Jia B, et al. Among authors: barndt rb. Hum Cell. 2020 Oct;33(4):1068-1080. doi: 10.1007/s13577-020-00410-1. Epub 2020 Aug 10. Hum Cell. 2020. PMID: 32779152

6

Targeted HAI-2 deletion causes excessive proteolysis with prolonged active prostasin and depletion of HAI-1 monomer in intestinal but not epidermal epithelial cells.

Barndt RB, Lee MJ, Huang N, Lu DD, Lee SC, Du PW, Chang CC, Tsai PB, Huang YK, Chang HM, Wang JK, Lai CH, Johnson MD, Lin CY. Barndt RB, et al. Hum Mol Genet. 2021 Sep 15;30(19):1833-1850. doi: 10.1093/hmg/ddab150. Hum Mol Genet. 2021. PMID: 34089062 Free PMC article.

7

The difference in the intracellular Arg/Lys-rich and EHLVY motifs contributes to distinct subcellular distribution of HAI-1 versus HAI-2.

Huang N, Barndt RB, Lu DD, Wang Q, Huang SM, Wang JK, Chang PY, Chen CY, Hu JM, Su HC, Johnson MD, Lin CY. Huang N, et al. Among authors: barndt rb. Hum Cell. 2022 Jan;35(1):163-178. doi: 10.1007/s13577-021-00632-x. Epub 2021 Oct 13. Hum Cell. 2022. PMID: 34643933

8

Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity.

Chiu YL, Wu YY, Barndt RB, Lin YW, Sytwo HP, Cheng A, Yang K, Chan KS, Wang JK, Johnson MD, Lin CY. Chiu YL, et al. Among authors: barndt rb. Genes Dis. 2020 Dec 9;9(4):1049-1061. doi: 10.1016/j.gendis.2020.12.001. eCollection 2022 Jul. Genes Dis. 2020. PMID: 35685459 Free PMC article.

9

Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytes.

Chen YW, Wang JK, Chou FP, Wu BY, Hsiao HC, Chiu H, Xu Z, Baksh ANH, Shi G, Kaul M, Barndt R, Shanmugam VK, Johnson MD, Lin CY. Chen YW, et al. Among authors: barndt r. J Invest Dermatol. 2014 Feb;134(2):405-414. doi: 10.1038/jid.2013.320. Epub 2013 Jul 26. J Invest Dermatol. 2014. PMID: 23900022 Free PMC article.

10

Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.

Deb TB, Coticchia CM, Barndt R, Zuo H, Dickson RB, Johnson MD. Deb TB, et al. Among authors: barndt r. Am J Physiol Cell Physiol. 2008 Aug;295(2):C365-77. doi: 10.1152/ajpcell.00449.2007. Epub 2008 Jun 18. Am J Physiol Cell Physiol. 2008. PMID: 18562482 Free PMC article.

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