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Increased delivery of chemotherapy to the vitreous by inhibition of the blood-retinal barrier.
Pascual-Pasto G, Olaciregui NG, Opezzo JAW, Castillo-Ecija H, Cuadrado-Vilanova M, Paco S, Rivero EM, Vila-Ubach M, Restrepo-Perdomo CA, Torrebadell M, Suñol M, Schaiquevich P, Mora J, Bramuglia GF, Chantada GL, Carcaboso AM. Pascual-Pasto G, et al. Among authors: chantada gl. J Control Release. 2017 Oct 28;264:34-44. doi: 10.1016/j.jconrel.2017.08.018. Epub 2017 Aug 19. J Control Release. 2017. PMID: 28830790
A phase I study of periocular topotecan in children with intraocular retinoblastoma.
Chantada GL, Fandino AC, Carcaboso AM, Lagomarsino E, de Davila MT, Guitter MR, Rose AB, Manzitti J, Bramuglia GF, Abramson DH. Chantada GL, et al. Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1492-6. doi: 10.1167/iovs.08-2737. Epub 2008 Oct 31. Invest Ophthalmol Vis Sci. 2009. PMID: 18978345 Clinical Trial.
Episcleral implants for topotecan delivery to the posterior segment of the eye.
Carcaboso AM, Chiappetta DA, Opezzo JA, Höcht C, Fandiño AC, Croxatto JO, Rubio MC, Sosnik A, Abramson DH, Bramuglia GF, Chantada GL. Carcaboso AM, et al. Among authors: chantada gl. Invest Ophthalmol Vis Sci. 2010 Apr;51(4):2126-34. doi: 10.1167/iovs.09-4050. Epub 2009 Oct 15. Invest Ophthalmol Vis Sci. 2010. PMID: 19834044
189 results