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Page 1
Discovery of Potent and Selective A2A Antagonists with Efficacy in Animal Models of Parkinson's Disease and Depression.
Basu S, Barawkar DA, Ramdas V, Naykodi M, Shejul YD, Patel M, Thorat S, Panmand A, Kashinath K, Bonagiri R, Prasad V, Bhat G, Quraishi A, Chaudhary S, Magdum A, Meru AV, Ghosh I, Bhamidipati RK, Raje AA, Madgula VLM, De S, Rouduri SR, Palle VP, Chugh A, Hariharan N, Mookhtiar KA. Basu S, et al. Among authors: chugh a. ACS Med Chem Lett. 2017 Jul 5;8(8):835-840. doi: 10.1021/acsmedchemlett.7b00175. eCollection 2017 Aug 10. ACS Med Chem Lett. 2017. PMID: 28835798 Free PMC article.
Discovery of a potent and selective small molecule hGPR91 antagonist.
Bhuniya D, Umrani D, Dave B, Salunke D, Kukreja G, Gundu J, Naykodi M, Shaikh NS, Shitole P, Kurhade S, De S, Majumdar S, Reddy SB, Tambe S, Shejul Y, Chugh A, Palle VP, Mookhtiar KA, Cully D, Vacca J, Chakravarty PK, Nargund RP, Wright SD, Graziano MP, Singh SB, Roy S, Cai TQ. Bhuniya D, et al. Among authors: chugh a. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3596-602. doi: 10.1016/j.bmcl.2011.04.091. Epub 2011 Apr 28. Bioorg Med Chem Lett. 2011. PMID: 21571530
Potent and Selective Inhibitors of Long Chain l-2-Hydroxy Acid Oxidase Reduced Blood Pressure in DOCA Salt-Treated Rats.
Barawkar DA, Meru A, Bandyopadhyay A, Banerjee A, Deshpande AM, Athare C, Koduru C, Khose G, Gundu J, Mahajan K, Patil P, Kandalkar SR, Niranjan S, Bhosale S, De S, Mukhopadhyay S, Chaudhary S, Koul S, Singh U, Chugh A, Palle VP, Mookhtiar KA, Vacca J, Chakravarty PK, Nargund RP, Wright SD, Roy S, Graziano MP, Singh SB, Cully D, Cai TQ. Barawkar DA, et al. Among authors: chugh a. ACS Med Chem Lett. 2011 Oct 7;2(12):919-23. doi: 10.1021/ml2001938. eCollection 2011 Dec 8. ACS Med Chem Lett. 2011. PMID: 24900281 Free PMC article.
A2B adenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives.
Basu S, Barawkar DA, Ramdas V, Waman Y, Patel M, Panmand A, Kumar S, Thorat S, Bonagiri R, Jadhav D, Mukhopadhyay P, Prasad V, Reddy BS, Goswami A, Chaturvedi S, Menon S, Quraishi A, Ghosh I, Dusange S, Paliwal S, Kulkarni A, Karande V, Thakre R, Bedse G, Rouduri S, Gundu J, Palle VP, Chugh A, Mookhtiar KA. Basu S, et al. Among authors: chugh a. Eur J Med Chem. 2017 Feb 15;127:986-996. doi: 10.1016/j.ejmech.2016.11.007. Epub 2016 Nov 8. Eur J Med Chem. 2017. PMID: 27842891
Design and synthesis of novel, potent and selective hypoxanthine analogs as adenosine A1 receptor antagonists and their biological evaluation.
Koul S, Ramdas V, Barawkar DA, Waman YB, Prasad N, Madadi SK, Shejul YD, Bonagiri R, Basu S, Menon S, Reddy SB, Chaturvedi S, Chennamaneni SR, Bedse G, Thakare R, Gundu J, Chaudhary S, De S, Meru AV, Palle V, Chugh A, Mookhtiar KA. Koul S, et al. Among authors: chugh a. Bioorg Med Chem. 2017 Mar 15;25(6):1963-1975. doi: 10.1016/j.bmc.2017.02.029. Epub 2017 Feb 16. Bioorg Med Chem. 2017. PMID: 28238512
Design and synthesis of novel xanthine derivatives as potent and selective A2B adenosine receptor antagonists for the treatment of chronic inflammatory airway diseases.
Basu S, Barawkar DA, Ramdas V, Patel M, Waman Y, Panmand A, Kumar S, Thorat S, Naykodi M, Goswami A, Reddy BS, Prasad V, Chaturvedi S, Quraishi A, Menon S, Paliwal S, Kulkarni A, Karande V, Ghosh I, Mustafa S, De S, Jain V, Banerjee ER, Rouduri SR, Palle VP, Chugh A, Mookhtiar KA. Basu S, et al. Among authors: chugh a. Eur J Med Chem. 2017 Jul 7;134:218-229. doi: 10.1016/j.ejmech.2017.04.014. Epub 2017 Apr 12. Eur J Med Chem. 2017. PMID: 28415011
Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain L-2-hydroxy acid oxidase.
Barawkar DA, Bandyopadhyay A, Deshpande A, Koul S, Kandalkar S, Patil P, Khose G, Vyas S, Mone M, Bhosale S, Singh U, De S, Meru A, Gundu J, Chugh A, Palle VP, Mookhtiar KA, Vacca JP, Chakravarty PK, Nargund RP, Wright SD, Roy S, Graziano MP, Cully D, Cai TQ, Singh SB. Barawkar DA, et al. Among authors: chugh a. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4341-7. doi: 10.1016/j.bmcl.2012.05.020. Epub 2012 May 11. Bioorg Med Chem Lett. 2012. PMID: 22658862
Discovery of liver-directed glucokinase activator having anti-hyperglycemic effect without hypoglycemia.
Deshpande AM, Bhuniya D, De S, Dave B, Vyavahare VP, Kurhade SH, Kandalkar SR, Naik KP, Kobal BS, Kaduskar RD, Basu S, Jain V, Patil P, Chaturvedi Joshi S, Bhat G, Raje AA, Reddy S, Gundu J, Madgula V, Tambe S, Shitole P, Umrani D, Chugh A, Palle VP, Mookhtiar KA. Deshpande AM, et al. Among authors: chugh a. Eur J Med Chem. 2017 Jun 16;133:268-286. doi: 10.1016/j.ejmech.2017.03.042. Epub 2017 Mar 24. Eur J Med Chem. 2017. PMID: 28390958
Intermittent claudication: an overview.
Meru AV, Mittra S, Thyagarajan B, Chugh A. Meru AV, et al. Among authors: chugh a. Atherosclerosis. 2006 Aug;187(2):221-37. doi: 10.1016/j.atherosclerosis.2005.11.027. Epub 2005 Dec 28. Atherosclerosis. 2006. PMID: 16386260 Review.
531 results