Toulany M - Search Results

1

AKT2 suppresses pro-survival autophagy triggered by DNA double-strand breaks in colorectal cancer cells.

Seiwert N, Neitzel C, Stroh S, Frisan T, Audebert M, Toulany M, Kaina B, Fahrer J. Seiwert N, et al. Among authors: toulany m. Cell Death Dis. 2017 Aug 24;8(8):e3019. doi: 10.1038/cddis.2017.418. Cell Death Dis. 2017. PMID: 28837154 Free PMC article.

2

Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.

Toulany M, Kehlbach R, Florczak U, Sak A, Wang S, Chen J, Lobrich M, Rodemann HP. Toulany M, et al. Mol Cancer Ther. 2008 Jul;7(7):1772-81. doi: 10.1158/1535-7163.MCT-07-2200. Mol Cancer Ther. 2008. PMID: 18644989

3

2-Methoxyestradiol-induced radiosensitization is independent of SOD but depends on inhibition of Akt and DNA-PKcs activities.

Florczak U, Toulany M, Kehlbach R, Peter Rodemann H. Florczak U, et al. Among authors: toulany m. Radiother Oncol. 2009 Sep;92(3):334-8. doi: 10.1016/j.radonc.2009.06.005. Epub 2009 Jul 7. Radiother Oncol. 2009. PMID: 19589609

4

ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway.

Toulany M, Minjgee M, Kehlbach R, Chen J, Baumann M, Rodemann HP. Toulany M, et al. Radiother Oncol. 2010 Nov;97(2):338-45. doi: 10.1016/j.radonc.2010.03.008. Epub 2010 Mar 27. Radiother Oncol. 2010. PMID: 20347166

5

Autophagy contributes to resistance of tumor cells to ionizing radiation.

Chaachouay H, Ohneseit P, Toulany M, Kehlbach R, Multhoff G, Rodemann HP. Chaachouay H, et al. Among authors: toulany m. Radiother Oncol. 2011 Jun;99(3):287-92. doi: 10.1016/j.radonc.2011.06.002. Epub 2011 Jun 30. Radiother Oncol. 2011. PMID: 21722986

6

Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.

Toulany M, Lee KJ, Fattah KR, Lin YF, Fehrenbacher B, Schaller M, Chen BP, Chen DJ, Rodemann HP. Toulany M, et al. Mol Cancer Res. 2012 Jul;10(7):945-57. doi: 10.1158/1541-7786.MCR-11-0592. Epub 2012 May 17. Mol Cancer Res. 2012. PMID: 22596249 Free article.

7

Cisplatin-mediated radiosensitization of non-small cell lung cancer cells is stimulated by ATM inhibition.

Toulany M, Mihatsch J, Holler M, Chaachouay H, Rodemann HP. Toulany M, et al. Radiother Oncol. 2014 May;111(2):228-36. doi: 10.1016/j.radonc.2014.04.001. Epub 2014 May 21. Radiother Oncol. 2014. PMID: 24857596

8

Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells.

Holler M, Grottke A, Mueck K, Manes J, Jücker M, Rodemann HP, Toulany M. Holler M, et al. Among authors: toulany m. PLoS One. 2016 May 3;11(5):e0154745. doi: 10.1371/journal.pone.0154745. eCollection 2016. PLoS One. 2016. PMID: 27137757 Free PMC article.

9

Akt1 and Akt3 but not Akt2 through interaction with DNA-PKcs stimulate proliferation and post-irradiation cell survival of K-RAS-mutated cancer cells.

Toulany M, Maier J, Iida M, Rebholz S, Holler M, Grottke A, Jüker M, Wheeler DL, Rothbauer U, Rodemann HP. Toulany M, et al. Cell Death Discov. 2017 Oct 30;3:17072. doi: 10.1038/cddiscovery.2017.72. eCollection 2017. Cell Death Discov. 2017. PMID: 29090098 Free PMC article.

10

Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner.

Mueck K, Rebholz S, Harati MD, Rodemann HP, Toulany M. Mueck K, et al. Among authors: toulany m. Int J Mol Sci. 2017 Nov 20;18(11):2473. doi: 10.3390/ijms18112473. Int J Mol Sci. 2017. PMID: 29156644 Free PMC article.

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