Wu H - Search Results

1

A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.

Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. Stöhr J, et al. Among authors: wu y, wu h. Nat Chem. 2017 Sep;9(9):874-881. doi: 10.1038/nchem.2754. Epub 2017 Apr 3. Nat Chem. 2017. PMID: 28837163 Free PMC article.

2

Zinc-binding structure of a catalytic amyloid from solid-state NMR.

Lee M, Wang T, Makhlynets OV, Wu Y, Polizzi NF, Wu H, Gosavi PM, Stöhr J, Korendovych IV, DeGrado WF, Hong M. Lee M, et al. Among authors: wu y, wu h. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6191-6196. doi: 10.1073/pnas.1706179114. Epub 2017 May 31. Proc Natl Acad Sci U S A. 2017. PMID: 28566494 Free PMC article.

3

De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures.

Dang B, Wu H, Mulligan VK, Mravic M, Wu Y, Lemmin T, Ford A, Silva DA, Baker D, DeGrado WF. Dang B, et al. Among authors: wu y, wu h. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10852-10857. doi: 10.1073/pnas.1710695114. Epub 2017 Sep 25. Proc Natl Acad Sci U S A. 2017. PMID: 28973862 Free PMC article.

4

Design of a Short Thermally Stable α-Helix Embedded in a Macrocycle.

Wu H, Acharyya A, Wu Y, Liu L, Jo H, Gai F, DeGrado WF. Wu H, et al. Among authors: wu y. Chembiochem. 2018 May 4;19(9):902-906. doi: 10.1002/cbic.201800026. Epub 2018 Mar 22. Chembiochem. 2018. PMID: 29417711 Free PMC article.

5

Building and Breaking Bonds via a Compact S-Propargyl-Cysteine to Chemically Control Enzymes and Modify Proteins.

Liu J, Cheng R, Wu H, Li S, Wang PG, DeGrado WF, Rozovsky S, Wang L. Liu J, et al. Among authors: wu h. Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12702-12706. doi: 10.1002/anie.201806197. Epub 2018 Sep 5. Angew Chem Int Ed Engl. 2018. PMID: 30118570 Free PMC article.

6

Proximity-enhanced SuFEx chemical cross-linker for specific and multitargeting cross-linking mass spectrometry.

Yang B, Wu H, Schnier PD, Liu Y, Liu J, Wang N, DeGrado WF, Wang L. Yang B, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11162-11167. doi: 10.1073/pnas.1813574115. Epub 2018 Oct 15. Proc Natl Acad Sci U S A. 2018. PMID: 30322930 Free PMC article.

7

Exposing the Nucleation Site in α-Helix Folding: A Joint Experimental and Simulation Study.

Acharyya A, Ge Y, Wu H, DeGrado WF, Voelz VA, Gai F. Acharyya A, et al. Among authors: wu h. J Phys Chem B. 2019 Feb 28;123(8):1797-1807. doi: 10.1021/acs.jpcb.8b12220. Epub 2019 Feb 14. J Phys Chem B. 2019. PMID: 30694671 Free PMC article.

8

Glutamine Side Chain ¹³C═¹⁸O as a Nonperturbative IR Probe of Amyloid Fibril Hydration and Assembly.

Wu H, Saltzberg DJ, Kratochvil HT, Jo H, Sali A, DeGrado WF. Wu H, et al. J Am Chem Soc. 2019 May 8;141(18):7320-7326. doi: 10.1021/jacs.9b00577. Epub 2019 Apr 24. J Am Chem Soc. 2019. PMID: 30998340 Free PMC article.

9

In vitro 0N4R tau fibrils contain a monomorphic β-sheet core enclosed by dynamically heterogeneous fuzzy coat segments.

Dregni AJ, Mandala VS, Wu H, Elkins MR, Wang HK, Hung I, DeGrado WF, Hong M. Dregni AJ, et al. Among authors: wu h. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16357-16366. doi: 10.1073/pnas.1906839116. Epub 2019 Jul 29. Proc Natl Acad Sci U S A. 2019. PMID: 31358628 Free PMC article.

10

Inclusion of the C-Terminal Domain in the β-Sheet Core of Heparin-Fibrillized Three-Repeat Tau Protein Revealed by Solid-State Nuclear Magnetic Resonance Spectroscopy.

Dregni AJ, Wang HK, Wu H, Duan P, Jin J, DeGrado WF, Hong M. Dregni AJ, et al. Among authors: wu h. J Am Chem Soc. 2021 May 26;143(20):7839-7851. doi: 10.1021/jacs.1c03314. Epub 2021 May 13. J Am Chem Soc. 2021. PMID: 33983722 Free PMC article.

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