Smith EC - Search Results

1

2-Amino- and 2-guanidino-1,2,3,4-tetrahydro-1,4-epoxynaphthalenes as conformationally defined analogues of alpha-adrenergic agents.

Smith EC, Riley TN, Borne RF, Waters IW. Smith EC, et al. J Med Chem. 1987 Jun;30(6):1105-10. doi: 10.1021/jm00389a023. J Med Chem. 1987. PMID: 2884315

2

Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones.

McQuaid LA, Smith EC, South KK, Mitch CH, Schoepp DD, True RA, Calligaro DO, O'Malley PJ, Lodge D, Ornstein PL. McQuaid LA, et al. Among authors: smith ec. J Med Chem. 1992 Sep 4;35(18):3319-24. doi: 10.1021/jm00096a002. J Med Chem. 1992. PMID: 1382133

3

Synthesis and biological activity of structural analogues of the anticancer benzophenanthridine alkaloid nitidine chloride.

Cushman M, Mohan P, Smith EC. Cushman M, et al. Among authors: smith ec. J Med Chem. 1984 Apr;27(4):544-7. doi: 10.1021/jm00370a021. J Med Chem. 1984. PMID: 6708057

4

Design and synthesis of a novel series of 1,2-disubstituted cyclopentanes as small, potent potentiators of 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid (AMPA) receptors.

Shepherd TA, Aikins JA, Bleakman D, Cantrell BE, Rearick JP, Simon RL, Smith EC, Stephenson GA, Zimmerman DM, Mandelzys A, Jarvie KR, Ho K, Deverill M, Kamboj RK. Shepherd TA, et al. Among authors: smith ec. J Med Chem. 2002 May 9;45(10):2101-11. doi: 10.1021/jm0105474. J Med Chem. 2002. PMID: 11985477

5

3-Phenyl-4-hydroxyquinolin-2(1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex.

McQuaid LA, Smith EC, Lodge D, Pralong E, Wikel JH, Calligaro DO, O'Malley PJ. McQuaid LA, et al. Among authors: smith ec. J Med Chem. 1992 Sep 4;35(18):3423-5. doi: 10.1021/jm00096a019. J Med Chem. 1992. PMID: 1326635 No abstract available.

6

Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains.

Meanwell NA, Pearce BC, Roth HR, Smith EC, Wedding DL, Wright JJ, Buchanan JO, Baryla UM, Gamberdella M, Gillespie E, et al. Meanwell NA, et al. Among authors: smith ec. J Med Chem. 1992 Jul 10;35(14):2672-87. doi: 10.1021/jm00092a019. J Med Chem. 1992. PMID: 1321910

7

Carbocyclic[g]indole inhibitors of human nonpancreatic s-PLA2.

Sawyer JS, Beight DW, Smith EC, Snyder DW, Chastain MK, Tielking RL, Hartley LW, Carlson DG. Sawyer JS, et al. Among authors: smith ec. J Med Chem. 2005 Feb 10;48(3):893-6. doi: 10.1021/jm0401309. J Med Chem. 2005. PMID: 15689175

8

Inhibitors of blood platelet cAMP phosphodiesterase. 3. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives with enhanced aqueous solubility.

Meanwell NA, Dennis RD, Roth HR, Rosenfeld MJ, Smith EC, Wright JJ, Buchanan JO, Brassard CL, Gamberdella M, Gillespie E, et al. Meanwell NA, et al. Among authors: smith ec. J Med Chem. 1992 Jul 10;35(14):2688-96. doi: 10.1021/jm00092a020. J Med Chem. 1992. PMID: 1321911

9

Synthesis and 5 alpha-reductase inhibitory activity of 8-substituted benzo[f]quinolinones derived from palladium mediated coupling reactions.

Smith EC, McQuaid LA, Goode RL, McNulty AM, Neubauer BL, Rocco VP, Audia JE. Smith EC, et al. Bioorg Med Chem Lett. 1998 Feb 17;8(4):395-8. doi: 10.1016/s0960-894x(98)00035-3. Bioorg Med Chem Lett. 1998. PMID: 9871692

10

1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

Meanwell NA, Roth HR, Smith EC, Wedding DL, Wright JJ, Fleming JS, Gillespie E. Meanwell NA, et al. Among authors: smith ec. J Med Chem. 1991 Sep;34(9):2906-16. doi: 10.1021/jm00113a033. J Med Chem. 1991. PMID: 1654430

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