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Grade-specific expression of insulin-like growth factor-binding proteins-2, -3, and -5 in astrocytomas: IGFBP-3 emerges as a strong predictor of survival in patients with newly diagnosed glioblastoma.
Santosh V, Arivazhagan A, Sreekanthreddy P, Srinivasan H, Thota B, Srividya MR, Vrinda M, Sridevi S, Shailaja BC, Samuel C, Prasanna KV, Thennarasu K, Balasubramaniam A, Chandramouli BA, Hegde AS, Somasundaram K, Kondaiah P, Rao MR. Santosh V, et al. Cancer Epidemiol Biomarkers Prev. 2010 Jun;19(6):1399-408. doi: 10.1158/1055-9965.EPI-09-1213. Epub 2010 May 25. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20501753
Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2.
Suvasini R, Shruti B, Thota B, Shinde SV, Friedmann-Morvinski D, Nawaz Z, Prasanna KV, Thennarasu K, Hegde AS, Arivazhagan A, Chandramouli BA, Santosh V, Somasundaram K. Suvasini R, et al. Among authors: santosh v. J Biol Chem. 2011 Jul 22;286(29):25882-90. doi: 10.1074/jbc.M110.178012. Epub 2011 May 25. J Biol Chem. 2011. PMID: 21613208 Free PMC article.
248 results