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Page 1
Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation.
Meier JC, Tallant C, Fedorov O, Witwicka H, Hwang SY, van Stiphout RG, Lambert JP, Rogers C, Yapp C, Gerstenberger BS, Fedele V, Savitsky P, Heidenreich D, Daniels DL, Owen DR, Fish PV, Igoe NM, Bayle ED, Haendler B, Oppermann UCT, Buffa F, Brennan PE, Müller S, Gingras AC, Odgren PR, Birnbaum MJ, Knapp S. Meier JC, et al. ACS Chem Biol. 2017 Oct 20;12(10):2619-2630. doi: 10.1021/acschembio.7b00481. Epub 2017 Sep 12. ACS Chem Biol. 2017. PMID: 28849908 Free PMC article.
Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
Bennett J, Fedorov O, Tallant C, Monteiro O, Meier J, Gamble V, Savitsky P, Nunez-Alonso GA, Haendler B, Rogers C, Brennan PE, Müller S, Knapp S. Bennett J, et al. J Med Chem. 2016 Feb 25;59(4):1642-7. doi: 10.1021/acs.jmedchem.5b00458. Epub 2015 May 20. J Med Chem. 2016. PMID: 25974391 Free PMC article.
Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins.
Igoe N, Bayle ED, Tallant C, Fedorov O, Meier JC, Savitsky P, Rogers C, Morias Y, Scholze S, Boyd H, Cunoosamy D, Andrews DM, Cheasty A, Brennan PE, Müller S, Knapp S, Fish PV. Igoe N, et al. Among authors: meier jc. J Med Chem. 2017 Aug 24;60(16):6998-7011. doi: 10.1021/acs.jmedchem.7b00611. Epub 2017 Aug 10. J Med Chem. 2017. PMID: 28714688 Free article.
Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.
Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Che KH, Bannister A, Robson S, Kumar U, Parr N, Lee K, Lugo D, Jeffrey P, Taylor S, Vecellio ML, Bountra C, Brennan PE, O'Mahony A, Velichko S, Müller S, Hay D, Daniels DL, Urh M, La Thangue NB, Kouzarides T, Prinjha R, Schwaller J, Knapp S. Picaud S, et al. Cancer Res. 2015 Dec 1;75(23):5106-5119. doi: 10.1158/0008-5472.CAN-15-0236. Epub 2015 Nov 9. Cancer Res. 2015. PMID: 26552700 Free PMC article.
Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.
Bouché L, Christ CD, Siegel S, Fernández-Montalván AE, Holton SJ, Fedorov O, Ter Laak A, Sugawara T, Stöckigt D, Tallant C, Bennett J, Monteiro O, Díaz-Sáez L, Siejka P, Meier J, Pütter V, Weiske J, Müller S, Huber KVM, Hartung IV, Haendler B. Bouché L, et al. J Med Chem. 2017 May 11;60(9):4002-4022. doi: 10.1021/acs.jmedchem.7b00306. Epub 2017 May 1. J Med Chem. 2017. PMID: 28402630 Free PMC article.
Patient-reported disease control versus overall symptom severity as global metrics of chronic rhinosinusitis disease status.
Cotter RA, Garcia JT, Alsayed A, Schneider S, Liu DT, Eckl-Dorna J, Houssein FA, Boparai RS, Parail NA, Chu MM, Meier JC, Alsaleh S, Phillips KM, Sedaghat AR. Cotter RA, et al. Among authors: meier jc. Int Forum Allergy Rhinol. 2024 Sep 13. doi: 10.1002/alr.23435. Online ahead of print. Int Forum Allergy Rhinol. 2024. PMID: 39269197
Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications.
Helm M, Bohnsack MT, Carell T, Dalpke A, Entian KD, Ehrenhofer-Murray A, Ficner R, Hammann C, Höbartner C, Jäschke A, Jeltsch A, Kaiser S, Klassen R, Leidel SA, Marx A, Mörl M, Meier JC, Meister G, Rentmeister A, Rodnina M, Roignant JY, Schaffrath R, Stadler P, Stafforst T. Helm M, et al. Among authors: meier jc. ACS Chem Biol. 2023 Dec 15;18(12):2441-2449. doi: 10.1021/acschembio.3c00586. Epub 2023 Nov 14. ACS Chem Biol. 2023. PMID: 37962075 Review.
Patient perspectives on recall period and response options in patient-reported outcome measures for chronic rhinosinusitis symptomatology: An international multi-centered study.
Sedaghat AR, Derbarsegian A, Yu VT, Alsayed A, Bitner BF, Yeom B, Liu DT, Schneider S, Adams SM, Houssein FA, Walters ZA, Tripathi S, Walker VL, Singerman KW, Meier JC, Kim R, Kuan EC, Alsaleh S, Phillips KM. Sedaghat AR, et al. Among authors: meier jc. Int Forum Allergy Rhinol. 2024 May;14(5):898-908. doi: 10.1002/alr.23280. Epub 2023 Oct 3. Int Forum Allergy Rhinol. 2024. PMID: 37788156
90 results