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Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.
Mettananda S, Fisher CA, Hay D, Badat M, Quek L, Clark K, Hublitz P, Downes D, Kerry J, Gosden M, Telenius J, Sloane-Stanley JA, Faustino P, Coelho A, Doondeea J, Usukhbayar B, Sopp P, Sharpe JA, Hughes JR, Vyas P, Gibbons RJ, Higgs DR. Mettananda S, et al. Nat Commun. 2017 Sep 4;8(1):424. doi: 10.1038/s41467-017-00479-7. Nat Commun. 2017. PMID: 28871148 Free PMC article.
24 h Activity Guidelines in Children and Adolescents: A Prevalence Survey in Asia-Pacific Cities.
Quah PL, Loo BKG, Mettananda S, Dassanayake S, Chia MYH, Chua TBK, Tan TSZ, Chan PC, But BW, Fu AC, Wong SM, Nagano N, Morioka I, Kumar S, Nair MKC, Tan KH. Quah PL, et al. Among authors: mettananda s. Int J Environ Res Public Health. 2023 Jul 19;20(14):6403. doi: 10.3390/ijerph20146403. Int J Environ Res Public Health. 2023. PMID: 37510635 Free PMC article.
Molecular Basis and Genetic Modifiers of Thalassemia.
Mettananda S, Higgs DR. Mettananda S, et al. Hematol Oncol Clin North Am. 2018 Apr;32(2):177-191. doi: 10.1016/j.hoc.2017.11.003. Hematol Oncol Clin North Am. 2018. PMID: 29458725 Review.
Direct correction of haemoglobin E β-thalassaemia using base editors.
Badat M, Ejaz A, Hua P, Rice S, Zhang W, Hentges LD, Fisher CA, Denny N, Schwessinger R, Yasara N, Roy NBA, Issa F, Roy A, Telfer P, Hughes J, Mettananda S, Higgs DR, Davies JOJ. Badat M, et al. Among authors: mettananda s. Nat Commun. 2023 Apr 19;14(1):2238. doi: 10.1038/s41467-023-37604-8. Nat Commun. 2023. PMID: 37076455 Free PMC article.
73 results