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Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes.
Maekawa M, Watanabe A, Iwayama Y, Kimura T, Hamazaki K, Balan S, Ohba H, Hisano Y, Nozaki Y, Ohnishi T, Toyoshima M, Shimamoto C, Iwamoto K, Bundo M, Osumi N, Takahashi E, Takashima A, Yoshikawa T. Maekawa M, et al. Among authors: ohba h. Transl Psychiatry. 2017 Sep 5;7(9):e1229. doi: 10.1038/tp.2017.182. Transl Psychiatry. 2017. PMID: 28872641 Free PMC article.
Excessive ingestion of long-chain polyunsaturated fatty acids during developmental stage causes strain- and sex-dependent eye abnormalities in mice.
Maekawa M, Iwayama Y, Watanabe A, Nozaki Y, Ohnishi T, Ohba H, Toyoshima M, Hamazaki K, Osumi N, Aruga J, Yoshikawa T. Maekawa M, et al. Among authors: ohba h. Biochem Biophys Res Commun. 2010 Nov 12;402(2):431-7. doi: 10.1016/j.bbrc.2010.10.051. Epub 2010 Oct 15. Biochem Biophys Res Commun. 2010. PMID: 20951676
Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.
Ohnishi T, Yamada K, Watanabe A, Ohba H, Sakaguchi T, Honma Y, Iwayama Y, Toyota T, Maekawa M, Watanabe K, Detera-Wadleigh SD, Wakana S, Yoshikawa T. Ohnishi T, et al. Among authors: ohba h. PLoS One. 2011;6(12):e29499. doi: 10.1371/journal.pone.0029499. Epub 2011 Dec 29. PLoS One. 2011. PMID: 22242126 Free PMC article.
Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies.
Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada Y, Kobayashi T, Yoshikawa T. Shimamoto C, et al. Among authors: ohba h. Hum Mol Genet. 2014 Dec 15;23(24):6495-511. doi: 10.1093/hmg/ddu369. Epub 2014 Jul 15. Hum Mol Genet. 2014. PMID: 25027319 Free PMC article.
Thiosulfate promotes hair growth in mouse model.
Maekawa M, Ohnishi T, Balan S, Hisano Y, Nozaki Y, Ohba H, Toyoshima M, Shimamoto C, Tabata C, Wada Y, Yoshikawa T. Maekawa M, et al. Among authors: ohba h. Biosci Biotechnol Biochem. 2019 Jan;83(1):114-122. doi: 10.1080/09168451.2018.1518705. Epub 2018 Sep 10. Biosci Biotechnol Biochem. 2019. PMID: 30200826
A potential role of fatty acid binding protein 4 in the pathophysiology of autism spectrum disorder.
Maekawa M, Ohnishi T, Toyoshima M, Shimamoto-Mitsuyama C, Hamazaki K, Balan S, Wada Y, Esaki K, Takagai S, Tsuchiya KJ, Nakamura K, Iwata Y, Nara T, Iwayama Y, Toyota T, Nozaki Y, Ohba H, Watanabe A, Hisano Y, Matsuoka S, Tsujii M, Mori N, Matsuzaki H, Yoshikawa T. Maekawa M, et al. Among authors: ohba h. Brain Commun. 2020 Sep 10;2(2):fcaa145. doi: 10.1093/braincomms/fcaa145. eCollection 2020. Brain Commun. 2020. PMID: 33225276 Free PMC article.
Peroxisome proliferator-activated receptor α as a novel therapeutic target for schizophrenia.
Wada Y, Maekawa M, Ohnishi T, Balan S, Matsuoka S, Iwamoto K, Iwayama Y, Ohba H, Watanabe A, Hisano Y, Nozaki Y, Toyota T, Shimogori T, Itokawa M, Kobayashi T, Yoshikawa T. Wada Y, et al. Among authors: ohba h. EBioMedicine. 2020 Dec;62:103130. doi: 10.1016/j.ebiom.2020.103130. Epub 2020 Dec 2. EBioMedicine. 2020. PMID: 33279456 Free PMC article.
391 results